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  • Action of serotonin reuptake inhibitors

    Depression in adults: recognition and management Subscription

    Pharmacists and healthcare professionals should be able to recognise the symptoms of depression in people who use their services and direct them towards accessing treatment. This article examines how a diagnosis of depression is made, the pharmacological and non-pharmacological treatments available, specific considerations for different patient groups, self-management approaches, and the role of the pharmacy team in managing and supporting patients who have symptoms of depression.

  • Micrograph of multiple myeloma tumour cells (green) and bone cells (red) growing on a scaffold made of silk protein (purple), designed to resemble bone material

    Multiple myeloma: pharmacological management

    Although multiple myeloma is currently regarded as being incurable in the majority of patients, the outlook for patients diagnosed with the condition has improved markedly over the last 40 years, with survival rates quadrupling. Significant advances in both treatment and supportive therapies have contributed to these improved outcomes and are discussed in this article.

  • Micrograph of Clostridium difficile bacteria

    Clostridium difficile: diagnosis and treatment update

    There are around 12,000 cases of Clostridium difficile infection (CDI) each year in the UK and during 1999 to 2007, deaths from CDI peaked at around 4,000 per year. This article summarises diagnosis and management, as well as the current therapeutic options for CDI, including faecal microbiota transplant.

  • coloured scanning electron micrograph (SEM) of bacterial blood infection (sepsis) caused by a rod shaped bacterium (blue)

    Sepsis: an update on identification and management Subscription

    All healthcare professionals, including pharmacists, should be aware of the clinical features and management of sepsis. This article summarises the recent changes in the definition of sepsis in adults, as well as its management.

  • Testing for blood clotting

    How to identify causes of a subtherapeutic INR Subscription

    Pharmacists and healthcare professionals are often involved in the management of patients with subtherapeutic international normalised ratios (INRs), the cause of which is important to identify because this will affect decisions and the subsequent management of the patient.

  • Boy with Down's Syndrome listens to a healthcare worker

    Reducing antipsychotic prescribing in people with learning disabilities Subscription

    Pharmacists and healthcare professionals are ideally placed to review and reduce inappropriate prescribing of psychotropic medicines in people with learning disabilities safely and effectively.

  • X-ray of the intestines of a patient with Crohn's disease

    Biosimilars and inflammatory bowel disease: a switch programme using CT-P13 Subscription

    How to plan and manage switching patients from a biologic to a biosimilar in inflammatory bowel disease, using the University Hospital Southampton NHS Foundation Trust’s experience as an example.

  • Illustration antibiotic destroying bacteria

    Principles of initiating antimicrobial therapy and empiric prescribing Subscription

    Healthcare professionals should be aware of the principles of antimicrobial treatment and the need to reduce inappropriate prescribing to retain the effectiveness of drugs currently available.

  • Urticaria rash on the upper chest of a woman

    Chronic spontaneous urticaria: clinical features, diagnosis and management Subscription

    Defined as the non-inducible recurrence of wheals, angioedema or both for six weeks or more, chronic spontaneous urticaria is a difficult to diagnose and debilitating skin condition. Pharmacists should be aware of the clinical features in order to identify and manage this condition effectively.

  • Close up of a leg with livedo reticular is

    Antiphospholipid syndrome: pathophysiology, diagnosis and treatment Subscription

    How antiphospholipid syndrome, also known as Hughes syndrome, is diagnosed and the appropriate therapeutic options for its management.

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