Consultant pharmacist, anti-infectives, at University Hospital Southampton NHS Foundation Trust
Microbiology nuts and bolts (Book review)Subscription
‘Microbiology nuts and bolts’ by David Garner. Pp 282. Price £27.99. Charleston: CreateSpace Independent Publishing Platform: 2013. ISBN 978 1 484 123911
The right drug for the right bugSubscription
By Hayley Wickens and Paul Wade Infection is a leading cause of morbidity and mortality in hospitals and empiric use of antibacterials is common. However, prescribers face a dilemma: initial antibacterial therapy must cover all the likely infective organisms for the presentation (inadequate initial therapy is associated with a poor outcome) but excessive use of broad-spectrum agents contributes to the selection of antibacterial-resistant organisms that
Understanding antibiotic resistanceSubscription
Antibiotic resistance can be described as microbiological or clinical. Microbiological resistance exists when an organism possesses any resistance mechanism (see Panel 1 for examples). Clinical resistance can be explained as failure to achieve a concentration of antimicrobial that inhibits the growth of the organism in a particular tissue or fluid.