Although multiple myeloma is currently regarded as being incurable in the majority of patients, the outlook for patients diagnosed with the condition has improved markedly over the last 40 years, with survival rates quadrupling. Significant advances in both treatment and supportive therapies have contributed to these improved outcomes and are discussed in this article.
There are around 12,000 cases of Clostridium difficile infection (CDI) each year in the UK and during 1999 to 2007, deaths from CDI peaked at around 4,000 per year. This article summarises diagnosis and management, as well as the current therapeutic options for CDI, including faecal microbiota transplant.
Sepsis: an update on identification and management Subscription
All healthcare professionals, including pharmacists, should be aware of the clinical features and management of sepsis. This article summarises the recent changes in the definition of sepsis in adults, as well as its management.
How to identify causes of a subtherapeutic INRSubscription
Pharmacists and healthcare professionals are often involved in the management of patients with subtherapeutic international normalised ratios (INRs), the cause of which is important to identify because this will affect decisions and the subsequent management of the patient.
Pharmacists and healthcare professionals are ideally placed to review and reduce inappropriate prescribing of psychotropic medicines in people with learning disabilities safely and effectively.
How to plan and manage switching patients from a biologic to a biosimilar in inflammatory bowel disease, using the University Hospital Southampton NHS Foundation Trust’s experience as an example.
Healthcare professionals should be aware of the principles of antimicrobial treatment and the need to reduce inappropriate prescribing to retain the effectiveness of drugs currently available.
Defined as the non-inducible recurrence of wheals, angioedema or both for six weeks or more, chronic spontaneous urticaria is a difficult to diagnose and debilitating skin condition. Pharmacists should be aware of the clinical features in order to identify and manage this condition effectively.
How antiphospholipid syndrome, also known as Hughes syndrome, is diagnosed and the appropriate therapeutic options for its management.
Chronic obstructive pulmonary disease: clinical phenotypes and implications for managementSubscription
Phenotyping patients with chronic obsructive pulmonary disease allows their separation into distinct categories that differentiate their prognosis and response to treatment, producing clinically meaningful outcomes.
The role of non-statin drugs, including ezetimibe, fibrates, bile acid binders, nicotinic acid derivatives, omega-3 fatty acid supplements and PCSK9 inhibitors, for the management of dyslipidaemia in adults.
Bipolar disorder and its implications for women of childbearing age, with a focus on the use of valproate and how this compares to other available pharmacologic treatments.
How patients on anticoagulants can be effectively managed in the perioperative period, including the evidence for the need for ‘bridging’ anticoagulation therapy and introduction of direct oral anticoagulants.
CLUSTER 1. Expert Professional Practice
CLUSTER 2. Collaborative Working Relationships
CLUSTER 1. Patient and Pharmaceutical Care
CLUSTER 2. Professional Practice Competencies
CLUSTER 3. Personal Practice Competencies
CLUSTER 4: Management and organisation