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Medicines shortages

MHRA advises health professionals on supply of clobazam for epilepsy

An epilepsy charity has updated its advice for health professionals after it emerged there was a supply problem with clobazam tablets in the UK.

It follows confirmation from the Medicines and Healthcare products Regulatory Agency (MHRA) that the licence to produce generic clobazam tablets, called Clobazam Auden, has been transferred to Accord Healthcare.

The charity Epilepsy Action has advised pharmacists that they should be able to get supplies from the wholesaler Alliance, according to Epilepsy Action.

Supplies of liquid clobazam suspension (Topclob) made by Martindale Pharma and Rosemont Pharma are also available.

The Department of Health has also advised that Sanofi is temporarily out of stock of its version of clobazam tablets, called Frisium. Pharmacists who do not have supplies of Frisium should direct patients to their GP, epilepsy nurse or epilepsy specialist for advice on switching to a generic.

  • This story was amended on 21st August to clarify that the MHRA had not advised health professionals on where to obtain clobazam tablets but had simply confirmed the licence transfer.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2017.20203409

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