Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Cancer

Using aspirin for six months or more reduces the risk of some gastrointestinal cancers, study finds

Long-term use of aspirin can reduce the risk of several major types of gastrointestinal cancer and some non-gastrointestinal cancers, a 10-year population-based study has found[1].

Researchers carried out a matched-cohort study of a territory-wide database from all public hospitals in Hong Kong. Patients with aspirin prescribed for at least six months between 2000 and 2004 were extracted and matched with non-users in a 1:2 ratio. The average duration of aspirin prescribed was 7.7 years and the median dose was 80mg.

Cancer occurred in 15.9% of the 618,884 subjects and lung cancer was the most common.

Long-term use of aspirin showed a 24% to 47% significant reduction of major cancers in the gastrointestinal tract, including colorectal (24%), liver (47%), oesophageal (47%), pancreatic (34%) and gastric (38%) cancer. For non-gastrointestinal cancers, long-term use of aspirin only showed a significant reduction for leukaemia, lung and prostate cancers.

“The findings demonstrate that the long-term use of aspirin can reduce the risk of developing many major cancers,” said Kelvin Tsoi, research associate professor at the Chinese University of Hong Kong and lead author of the study.

“What should be noted is the significance of the results for cancers within the digestive tract, where the reductions in cancer incidence were all very substantial, especially for liver and oesophageal cancer,” he added.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2017.20203844

Readers' comments (2)

  • It will be interesting to know how and why effect on gastrointestinal Cancer was the most significant, and the lowest Aspirin dose producing that cancer-protection impact.

    Unsuitable or offensive? Report this comment

  • HanaFayyad
    Read the abstract.............

    Unsuitable or offensive? Report this comment

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Biological Therapeutics

    Biological Therapeutics

    An introduction to the treatment of disease using biological medicines derived from living plant and animal tissues.

    £32.00Buy now
  • Pharmacy Case Studies

    Pharmacy Case Studies

    Understand the application of therapeutics in clinical practice with Pharmacy Case Studies. This book helps you to demonstrate the knowledge gained during your studies.

    £32.00Buy now
  • Integrated Pharmacy Case Studies

    Integrated Pharmacy Case Studies

    Over 90 case studies based on real life patient-care scenarios. Each case includes learning outcomes and references.

    £42.00Buy now
  • BNF and BNF for Children

    BNF and BNF for Children

    Now available as a 2 year print subscription to both the BNF and BNFC, ensuring you have the latest medicines information as it publishes and at a greatly reduced price.

    £250.00Buy now
  • BNF and BNF for Children

    BNF and BNF for Children

    Now available as a 1 year print subscription to both the BNF and BNFC, ensuring you have the latest medicines information as it publishes and at a greatly reduced price.

    £130.00Buy now
  • Disease Management

    Disease Management

    Disease Management covers the diseases commonly encountered in primary care by system, with common therapeutic issues. Includes case studies and self-assessment sections.

    £52.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • aspirin tablets close up

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.