Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

HIV/AIDS

HIV prevention vaginal ring found acceptable to adolescent girls

A vaginal ring containing the antiretroviral drug dapivirine had high adherence among young women, study finds

dapivirine-vaginal-ring-16

Source: International Partnership for Microbicides

The dapivirine vaginal ring is safe and acceptable for adolescent girls and young women, who account for 25% of new HIV infections in sub-Saharan Africa each year

Adolescent girls and young women account for 25% of new HIV infections in sub-Saharan Africa each year.

In research presented at the IAS Conference on HIV Science in Paris (25 July 2017), 96 sexually active girls aged 15–17 years in the USA were randomly assigned in a 3:1 ratio to use either a monthly placebo or a vaginal ring containing the antiviral dapivirine for six months[1]. Adherence to ring use was assessed through self-report, plasma dapivirine concentrations and residual levels in used rings.

The researchers found that 42% of girls said they removed the ring only to change it once a month and blood serum levels indicated adherence of 87% to the dapivirine ring. The rate of adverse events was similar between the two groups.

The team says the results show that the ring is safe and acceptable for use by adolescent girls and plan to study its use in a larger population of adolescent girls in Africa.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20203464

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • dapivirine-vaginal-ring-16

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.