Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Diabetes

Omega-3 fatty acids suppress type 1 diabetes in mice

Study results raise hope that omega-3 polyunsaturated fatty acids found in fish oil may be able to reverse type 1 diabetes.

Micrograph of the islets of Langerhans found in the pancreas

Source: Shutterstock.com

Researchers found that increasing levels of omega-3 PUFAs after the onset of diabetes reduced markers of autoimmunity, normalised glucose and insulin levels, and resulted in a full recovery of pancreatic islet function.

Although insulin enables people with type 1 diabetes (T1D) to control their blood glucose, it does not prevent the autoimmune attack and degeneration of pancreatic islets that cause the disease.

In research published in the Journal of Clinical Investigation (online, 4 April 2017)[1], a team explored the effects of omega-3 polyunsaturated fatty acids (PUFAs) — which are found in fish oil and are known for their anti-inflammatory properties — in non-obese diabetic mice.

The researchers discovered that increasing levels of omega-3 PUFAs after the onset of diabetes, either through nutritional supplementation or via gene therapy, reduced markers of autoimmunity, normalised glucose and insulin levels, and resulted in a full recovery of pancreatic islet function.

The results raise the hope of being able to use omega-3 PUFAs to prevent or reverse T1D in clinical settings, and possibly in other autoimmune conditions, the researchers conclude.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20202606

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Developing Your Prescribing Skills

    Developing Your Prescribing Skills

    Developing Your Prescribing Skills uses case studies, mind maps and feedback from experienced prescribers. It supplies practical advice on the issues facing prescribers in all types of practice.

    £22.00Buy now
  • Aromatherapy Science

    Aromatherapy Science

    Science-based aromatherapy information for healthcare professionals. Includes monographs on the commonly used essential oils.

    £42.00Buy now
  • Pharmacy Case Studies

    Pharmacy Case Studies

    Understand the application of therapeutics in clinical practice with Pharmacy Case Studies. This book helps you to demonstrate the knowledge gained during your studies.

    £32.00Buy now
  • Integrated Pharmacy Case Studies

    Integrated Pharmacy Case Studies

    Over 90 case studies based on real life patient-care scenarios. Each case includes learning outcomes and references.

    £42.00Buy now
  • FASTtrack: Complementary and Alternative Medicine

    FASTtrack: Complementary and Alternative Medicine

    A quick-start guide to all the main types of Complementary and Alternative Medicine, providing both theoretical and practical information.

    £24.00Buy now
  • Disease Management

    Disease Management

    Disease Management covers the diseases commonly encountered in primary care by system, with common therapeutic issues. Includes case studies and self-assessment sections.

    £52.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Micrograph of the islets of Langerhans found in the pancreas

Jobs you might like

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.