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Micrograph of Acinetobacter baumannii bacteria

Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitorSubscription

10 MAY 2017By , ,

Over the past decade, infections caused by multidrug-resistant Gram-negative organisms have increased. The limited availability in treatment options for these infections prompted both the UK to create a five-year antimicrobial resistance strategic plan to stimulate the development of new antibiotics, and the Infectious Diseases Society of America to call for ten new antimicrobial agents to be developed by 2020. Ceftazidime-avibactam is a combination of a third-generation ...

Fluoroscopic examination of gastrointestinal (GI) tract showing inflammatory bowel disease (IBD)

Management of patients with inflammatory bowel disease: current and future treatmentsSubscription

6 MAR 2017By ,

Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the gastrointestinal tract and affects patients’ quality of life. Treatment of IBD involves induction and maintenance of remission. Current available therapies include anti-inflammatory aminosalicylates and corticosteroids, immunosuppressive agents, antibiotics and biologic agents. Some patients are not fully responsive to conventional treatment or lose efficacy over time. Recently approved ...

All Review article

Woman breathes into a spirometre to check for COPD

Demonstrating the patient benefit and value for the NHS of community pharmacy: insight from the Community Pharmacy Future modelSubscription

4 APR 2017By , ,

In the face of funding and efficiency cuts to community pharmacy, the role of the sector is coming under increasing pressure. The importance of outcomes evidence (particularly health economic evidence) is being brought sharply into focus. The profession must come together to produce the evidence needed to justify the services provided by community pharmacy and to support its future development. This article uses the Community Pharmacy Future (CPF) project, and the services developed ...

Rows of over-the-counter (OTC) cough medicine

A new way to look at acute cough in the pharmacySubscription

31 MAR 2017By

Cough is the most common symptom for which people seek medical advice, and patients with cough frequently present to community pharmacy. Cough can be either acute or chronic. Acute cough, defined as being of less than three weeks’ duration, is often caused by viral respiratory tract infection and is probably one of the most common reasons for accessing healthcare in the community. For these infections, no antiviral treatment exists and antibiotics have been shown to be ineffective in ...

All Perspective article

Molecular model of C-reactive protein

Evaluating a point-of-care C-reactive protein test to support antibiotic prescribing decisions in a general practiceSubscription

By , , ,

C-reactive protein (CRP) is a marker of infection and inflammation. It is high in bacterial infections but very low or close to zero in viral infections. The National Institute for Health and Care Excellence (NICE), England and Wales’s health technology assessment body, has issued guidance on pneumonia in adults; it recommends point-of-care (POC) CRP analysers when clinical assessment is inconclusive. If the CRP level is less than 20mg/L, no antibiotics ...

Oral anticoagulant therapy and INR blood test monitor

Assessing the impact of a targeted pharmacist-led anticoagulant review clinicSubscription

By , , ,

Local guidance, supported by the 2014 National Institute for Health and Care Excellence (NICE) guideline CG180 for atrial fibrillation (AF), recommends that patients receiving inadequate anticoagulation with a vitamin K antagonist (VKA), including time in therapeutic range (TTR) of <65%, should be reassessed. These patients were identified by the anticoagulation monitoring service (AMS) and highlighted to GPs for review. However, up to 59.3% of patients received ...

Close-up of a person taking a dry-blood spot test

Integrating community pharmacy testing for hepatitis C with specialist careSubscription

By Ryan Buchanan, Pembe Hassan-Hicks, Kevin Noble, Leonie Grellier, Julie Parkes, Salim I Khakoo

Many patients with hepatitis C virus (HCV) infection lie undiagnosed and a significant proportion of patients that have been identified are disengaged from specialist services. The Isle of Wight (IOW) typifies this issue, with an estimated 200 undiagnosed patients with HCV infection and a small number of known cases engaged with specialist services. Aim: To reduce the burden of undiagnosed HCV on the IOW and link new diagnoses directly ...

Elderly man consults with a carer about his medicines

Pharmacy at home: service for frail older patients demonstrates medicines risk reduction and admission avoidanceSubscription

By , , ,

The Exeter Cluster Pharmacy (ECP) team is part of an integrated community health and social care service, providing domiciliary medicines optimisation to around 145,000 people. The service undertakes clinical medication reviews for frail older people at home, assessing their risk of medicine-related harm in order to reduce these risks and potentially prevent hospital admissions. Objective: An evaluation was completed in 2014 to assess the level of service the pharmacy ...

How useful are medicines helplines for patients discharged from hospital?Subscription

By , , Szn-Fang Li

This paper suggests that patient helplines support medicines optimisation by ensuring patients have easy access to pharmacy experts to discuss concerns about their medicines and improve the quality of their pharmaceutical care.

The package user test: a method for improving medicines packaging Subscription

By ,

This paper describes a new performance-based package user test that has the potential to improve drug package design and therefore reduce drug selection errors.

We are all part virus — the role of human endogenous retrovirusesSubscription

By ,

Viruses lurk in our genome and science is only now starting to understand the important role that they might play in health and disease. Kalliopi Dodou and Paul Whiteley explain.

Integrated examinations: supporting students with team-based learningSubscription

By , , ,

Jason Hall and colleagues explain how Manchester Pharmacy School is applying team-based learning to the MPharm course to integrate science and practice modules.

A review of Controlled Drug incidents reported to the NRLS over seven yearsSubscription

To describe the number and types of patient safety incidents involving Controlled Drugs reported to the National Reporting and Learning System (NRLS) and the role of Accountable Officers for CDs (AOs) in incident reporting and learning.

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