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Scott M Grundy

Scott M Grundy is professor of internal medicine at the Center for Human Nutrition and Department of Internal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Suite Y3.206 Dallas, TX 75390-9052, United States.

Recent stories

  • Statins and other cholesterol-lowering drugs are increasingly being used for primary prevention of atherosclerotic cardiovascular disease. In the image, micrograph of cholesterol crystals

    Primary prevention of cardiovascular disease with statins: assessing the evidence base behind clinical guidanceSubscription

    12 FEB 2016

    Statins and other cholesterol-lowering drugs are increasingly being used for primary prevention of atherosclerotic cardiovascular disease. Three lines of evidence inform the development of therapeutic goals for both drug and lifestyle intervention. This evidence reveals the following principles for cholesterol lowering in primary prevention: (a) ‘the more (lowering), the better’ for relative risk reduction, (b) ‘the lower, the better’ for absolute risk reduction, and (c) ‘the earlier, the be

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