Category list : Anti-infective agents
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Antimalaria drugs could be an effective treatment for Parkinson’s disease Subscription
Two antimalarials were found to activate a receptor in the brain that is involved in protecting neurons that are lost in Parkinson’s disease.
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Study examines feasibility of using antibiotics to manage appendicitis Subscription
Patients with uncomplicated acute appendicitis treated with antibiotics can recover without surgery but is the degree of treatment efficacy enough to change practice?
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Draft guidance on antibiotics to prevent infective endocarditis Subscription
The National Institute on Health and Care Excellence (NICE) has reviewed its 2008 guidance on the use of antibiotics to prevent infective endocarditis and has announced that new draft guidance on the subject will remain unchanged. A consultation on the draft guidance is available on the NICE website until 29 June 2015.
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Promixin indication and dose update Subscription
Promixin (colistimethate sodium; Profile Pharma) 1 million International Units (MIU), powder for solution for infusion, is now indicated for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options (as opposed to hospital acquired pneumonia and complicated urinary tract infections previously). In reflection, the standard adult dose has been increased to 9 MIU/day (from 6 MIU) and max ...
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Imatinib mimics physiological response to produce antimicrobial effects Subscription
The anti-cancer agent imatinib at very low doses mimics a physiological innate response to infection in the bone marrow, research shows.
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Alternative antibiotic regimens effective for resource-poor settings Subscription
A major research venture has yielded two antibiotic regimens for treating severe infections that can be administered in the outpatient setting.
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Mario Raviglione: an ambitious new strategy to end tuberculosis Subscription
To coincide with World Tuberculosis Day on 24 March, the World Health Organization has called for support to achieve an ambitious new 20-year strategy to end the tuberculosis epidemic by 2035. Mario Raviglione, director of the WHO’s Global TB Programme, discusses the tasks and challenges ahea
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Newborn deaths cut by cleaning umbilical stump with chlorhexidine, study finds Subscription
Chlorhexidine applied to the umbilical cord of newborns reduces the risk of infection of the umbilical stump by 50% and neonatal mortality by 12%, review finds.
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Pharmacist’s team wins £50,000 innovation prize for antibiotic prescribing app Subscription
Microbiology app that assists antibiotic prescribing wins national award.
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Rolling out hepatitis C treatments will be costly Subscription
The new generation of heptatitis C antivirals is highly effective, but the drugs’ expense will put pressure on healthcare providers.
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