Category list : Anti-infective agents
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Daklinza licence extension Subscription
Daklinza (daclatasvir; Bristol Myers Squibb), used in combination with other drugs to treat hepatitis C, has been approved for extended use for patients co-infected with HIV and also post liver transplantation by the European Medicines Agency.
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Peptide antiviral “a real step forward” in search for flu treatment Subscription
Ongoing mutations of influenza virus surface proteins mean a different flu vaccine must be used each year, but researchers think they may have found a novel antiviral drug that could protect against a variety of influenza strains.
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Serious side effect with quinolone antibiotics Subscription
A few weeks ago, I found myself in touch with a woman who was clearly unwell, with a lot of intractable peripheral pain, unable to work and unable to live a normal life. The symptoms had been of sudden onset and she associated them with a course of ciprofloxacin that she had been prescribed. The episode began 30 months before and, at the time of writing, is ongoing, with no signs of improvement. I had never heard of such an effect of ciprofloxacin and was initially somewhat sceptical. ...
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Targeting hepatitis C — how new treatments work Subscription
There are >185 million people with hepatitis C infection worldwide but new treatments mean that most people with access to therapy can now be cured.
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Antibiotic carries short-term increased risk of heart attack, finds ‘persuasive’ study Subscription
Clarithromycin carries an increased short-term risk of cardiac death and should be prescribed “with caution” to patients who already have a high cardiovascular risk, according to new research.
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Pre-exposure prophylaxis necessary to reduce HIV infection rate among MSM Subscription
Offering men who have sex with men antiretroviral therapy as pre-exposure prophylaxis is necessary if the UK is to achieve a marked reduction in the annual rate of HIV infections by the end of this decade, according to new research.
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Ibuprofen could provide alternative to antibiotics for uncomplicated UTIs
Two-thirds of women found ibuprofen to be sufficient treatment for uncomplicated infection.
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Antibiotic management is effective for uncomplicated appendicitis Subscription
Surgery may not be necessary for children with uncomplicated appendicitis, study shows.
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Resistance to 'last resort' antibiotic found in bacteria on British farms Subscription
Resistance to the antibiotic colistin has been found in samples of bacteria on three British farms, the Department for Environment, Food and Rural Affairs has confirmed.
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On-demand prophylaxis protects against HIV infection in at-risk men Subscription
Randomised trial shows pre-exposure prophylaxis reduced the risk of HIV transmission by 86%.
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