Category list : Antifungal agents
Pharmacists should make themselves familiar with the Antifungal Drug Interactions Database Subscription
In this time of growing antimicrobial resistance, we do not have unlimited ways to effectively treat a systemic infection. We must be antimicrobial stewards and use antimicrobials responsibly to preserve their effectiveness. This applies to antifungals too — not just antibiotics
Aspergillosis: causes, types and treatment Subscription
Aspergillus-related disease is rare, but results in high mortality rates. The limited treatment options and emerging antifungal drug resistance mean that accurate diagnosis and management is paramount.
How to improve antifungal stewardship Subscription
Selecting appropriate antifungal therapies and performing ongoing reviews of these therapies can help support antifungal stewardship efforts and help reduce antifungal resistance.
Pharmacists can provide treatment and advice for this common yeast infection.
Canesten range updated Subscription
Bayer is updating its range of Canesten products. There will be changes to the naming and packaging, with the updated products being introduced from July 2015 until early 2016. The active ingredients and product composition will remain the same.
Caneston Bifonazole interaction with warfarin Subscription
The summary of product characteristics for Canesten Bifonazole Once Daily 1% w/w Cream (Bayer) now warns of a potential interaction with warfarin. Limited data suggests that an interaction between topical bifonazole and warfarin may be possible, leading to increases in INR [international normalised ratio]. If bifonazole is used in a patient on warfarin therapy they should be appropriately monitored. Closer monitoring may be ...
FDA grants priority approval for new antifungal Subscription
Isavuconazonium sulfate, an antifungal developed by Astellas, has been given priority approval by the US Food and Drug Administration to treat serious infections.
Antifungal agents interactions app and databases Subscription
The Fungal Infection Trust and the National Aspergillosis Centre have developed a freely available online resource and app for iPhone, iPad and Android devices, which displays potential interactions between antifungal agents and other medicines. The collaboration supported the development of two databases, one for patients and
Noxafil now available Subscription
Noxafil (posaconazole) is now available from Merck Sharp & Dohme. Net price: Concentrate for solution for infusion 300mg, 1 x glass vial, £211; oral suspension 40mg/ml, 1 x 105ml bottle, £491.20; gastro-resistant tablets 100mg, 24 x tablets, £596.96, 96 x tablets, £2,387.85.
Pevaryl cream is not recommended during pregnancy Subscription
Pevaryl (econazole nitrate; Janssen-Cilag) topical cream 1% is not recommended during pregnancy, because there is low systemic absorption of econazole, according to the updated summary of product characteristics.