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Category list : Antiviral agents

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  • Fuzeon product update Subscription

    17 DEC 2015 15:38

    The summary of product characteristics of the HIV medication Fuzeon (enfuvirtide; Roche) powder for solution for injection has been updated to warn that as a peptide, enfuvirtide can cause cutaneous amyloidosis at the injection site.

  • Research found that pre-exposure prophylaxis, taken at the time of sexual activity, reduced the risk of HIV transmission by 86% compared with placebo among men who have sex with men. In the image, close up of Truveda pill used for pre-exposure prophylaxis

    On-demand prophylaxis protects against HIV infection in at-risk men Subscription

    9 DEC 2015 11:12

    Randomised trial shows pre-exposure prophylaxis reduced the risk of HIV transmission by 86%.

  • Researchers report that disulfiram, molecular structure pictured), a drug used to treat alcoholism, can reactivate latent HIV. The findings represent a step towards eliminating latent HIV

    Alcoholism drug could help eliminate dormant HIV Subscription

    27 NOV 2015 14:28

    Disulfiram treatment can reactivate latent HIV, which could help eliminate the cells harbouring the virus, report finds.

  • The number of people receiving HIV treatment reached 15.8 million in June 2015, up 2.2 million on the previous year, says a new report by UNAIDS. In the image, Michel Sibidé, executive director of UNAIDS

    People taking HIV drugs rises to almost 16 million, UNAIDs reports Subscription

    27 NOV 2015 12:47 By John Zarocostas

    The number of people receiving HIV treatment reached 15.8 million in June 2015, an increase of 2.2 million on the previous year, says a new report by UNAIDS.

  • Errors in the BNF for Children Subscription

    13 NOV 2015 14:40

    An error has been found in the new British National Formulary (BNF) for Children (2015–2016) regarding the indications of aciclovir. Some indications are omitted or are unclear.

  • Reyataz boosted regimen Subscription

    13 NOV 2015 8:58

    Ordinarily, treatment of HIV-1 with Reyataz (atazanavir; Bristol Myers Squibb) is boosted by co-administration with ritonavir. However, the summary of product characteristics has been updated to reflect that, under certain circumstances, ritonavir does not need to be co-administered, for example in patients with hepatic impairment. 

  • Sustiva oral solution discontinued Subscription

    16 OCT 2015 10:43

    Sustiva oral solution 30mg/ml (efavirenz), used to treat HIV infection, has been discontinued by Bristol Myers Squibb. The “capsule sprinkle” method has been upgraded to the primary dosing method for patients who cannot swallow pills. In addition, as a result of the Sustiva oral solution discontinuation, the paediatric indication for the Sustiva hard capsules and film coated tablets has been extended to include children from three months of age and weighing at least 3.5kg.

  • The evidence base for influenza drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) must be strengthened, says report. In the image, micrograph of H1N1 influenza virus particles

    Tamiflu and Relenza need a better evidence base for influenza, report finds Subscription

    15 OCT 2015 16:28 By Janna Lawrence

    The evidence base for influenza drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) must be strengthened, says a report from the Wellcome Trust and the Academy of Medical Sciences.

  • New World Health Organization guidelines recommend that antiretroviral therapy be initiated in everyone living with HIV, regardless of their CD4 cell counts, as soon as possible after diagnosis. In the image, nurse takes HIV blood test from a patient

    WHO recommends earlier use of antiretrovirals in HIV patients Subscription

    1 OCT 2015 15:38

    The World Health Organization has published new guidelines recommending that antiretroviral therapy is initiated in everyone living with HIV, regardless of their CD4 cell counts, as soon as possible after diagnosis. 

  • New experimental antiviral treatments are a viable option for post-exposure prophylaxis (PEP) against Ebola. In the image, healthcare workers from Guinea undergo training

    Accidental exposure to Ebola could be managed with antivirals Subscription

    3 SEP 2015 12:40

    Researchers in the UK tested a risk assessment and management plan for healthcare workers exposed to Ebola virus

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