Category list : Bacterial infections
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Managing fever in children
This learning resource outlines guideline-based recommendations for the management of children and young people with fever, including the appropriate use of over-the-counter analgesics, to support effective pharmacy consultations.
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IV antibiotics no more effective than oral for eradicating infection in cystic fibrosis patients, study suggests Subscription
Intravenous antibiotics are not superior to oral antibiotics for eradicating Pseudomonas aeruginosa in cystic fibrosis patients, according to a randomised controlled trial in Lancet Respiratory Medicine.
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Cefiderocol effective for carbapenem-resistant Gram-negative infections Subscription
The clinical and microbiological outcomes of cefiderocol, a new antibiotic, were similar to the best available therapy for patients with life-threatening carbapenem-resistant infections, a phase III study has suggested.
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Stuck in the 1950s: why UTI diagnosis badly needs an update Subscription
Urinary tract infections are the second most common reason for prescribing an antibiotic and, with antimicrobial stewardship a priority for the government, the stakes for accurate diagnosis are being raised ever higher.
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Clinical guidelines recommend dipstick tests for lower UTI diagnosis alongside two or more symptoms Subscription
Accurate diagnosis of a lower urinary tract infection in women aged under 65 years should be based on a positive dipstick test result for nitrite, alongside two or more urinary symptoms, new guidelines from the Scottish Intercollegiate Guidelines Network say.
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Would my son have his Lyme disease diagnosis without my mother's instinct? It's time we trusted our patients
Pharmacist Arlene Brailey continues to fight for better testing and diagnosis of Lyme disease, after a tick bite left her son chronically ill.
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Sepsis risk factors could help inform antimicrobial stewardship in primary care, study suggests Subscription
Risk of sepsis and benefit from antibiotics following a GP consultation for infection are more substantial among those who are older, frail or who have had a urinary tract infection, a study has found.
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Community management of pneumonia and suspected COVID-19
The COVID-19 pandemic has highlighted the importance of understanding the differences between viral and bacterial pneumonia, and how adult patients can be managed as they recover at home.
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Clinical pipeline of new antibiotics remains small, global report highlights Subscription
A quarter of clinical-stage antibiotics are supported by plans to ensure better access and good stewardship after launch compared to 7% in 2018, but the clinical pipeline of antibiotics for priority infections remains small, according to a report published by the Access to Medicine Foundation.
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Why the newly licensed antibiotic cefepime should be introduced to UK formularies Subscription
Healthcare trusts should consider introducing the antibiotic cefepime to their outpatient parenteral antimicrobial therapy services to tackle infections that are becoming resistant to carbapenem antibiotics.
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Only 25% of patients with a UTI give a urine sample to confirm diagnosis Subscription
Most patients with urinary tract infections receive antibiotics on the day of diagnosis, but just a quarter have evidence of a urine sample being taken in their electronic health records, study results show.
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Case-based learning: meningitis Subscription
Causes, diagnosis and initial management options for adults and children with meningitis.
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Antibiotics overused in emergency departments for suspected UTI Subscription
Over 60% of patients treated for a urinary tract infection lack evidence of the infection, a study carried out in a Birmingham emergency department has found.
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Reducing cephalosporin-related supply errors Subscription
Cephalosporins are a class of beta-lactam antimicrobials that exert bactericidal effects through disruption of the bacterial cell wall. These broad-spectrum antimicrobials have played a core role in the treatment of severe infections since their launch in the latter half of the 20th century. Early generation cephalosporins provide robust coverage of Gram-positive bacteria, while the newer third- and fourth-generations offer additional Gram-negative coverage, including Pseudomonas ...
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Treat UTIs early in older adults 'to minimise sepsis risk' Subscription
Delaying or withholding antibiotics in older adults with urinary tract infections is associated with an increased risk of bloodstream infection and all-cause mortality, research published in The BMJ has shown.
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Rolling out emergency treatment boxes for bacterial endophthalmitis Subscription
Bacterial endophthalmitis is a sight-threatening eye infection, which may occur after penetrating injuries and ocular procedures. Bacterial load in the eye can double within 30 minutes. For this reason, European guidelines recommend delivery of endophthalmitis treatment within one hour of presentation
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Study results show increased hydration can prevent recurrent cystitis Subscription
Increased water intake can help prevent cystitis and reduce antibiotic use in women with recurrent infections who drink less than 1.5 litres of fluid a day, study results have shown.
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Antibiotic-resistant bacteria responsible for over 33,000 deaths in Europe in 2015, study finds
Infections with antibiotic-resistant bacteria accounted for over 33,000 deaths across Europe in 2015, researchers from the European Centre for Disease Prevention and Control have calculated.
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Chlamydia-like STI could become next 'superbug' if testing does not improve, say sexual health experts Subscription
The British Association of Sexual Health and HIV has produced its first guideline for the diagnosis of a little known but common sexually transmitted infection called Mycoplasma genitalium, to address concerns that MG has the potential to become a “superbug” within 10 years.
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7-day antibiotic course ‘non-inferior’ to 14 days for treatment of Gram-negative bacteraemia Subscription
Research has shown that shorter antibiotic courses are not inferior to longer courses for the treatment of Gram-negative bacteraemia.