Tag : Ebola outbreak 2014
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Q&A: Conducting an Ebola vaccine trial in Guinea in record time Subscription
John-Arne Røttingen tells his story about the Ebola vaccine trial in Guinea, made possible through an unforeseen international collaboration and elaborates on why further collaboration is needed in the future.
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A pharmacist's journey through the Ebola epidemic
Pharmacist Claire Liew is currently volunteering at an Ebola treatment centre in Sierra Leone. She explains how the disease has affected everyday life.
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Viral cell entry holds clue to effective treatment of Ebola Subscription
Scientists have identified an important pathway used by the Ebola virus to gain entry into cells that may lead to new therapeutic approaches.
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Ebola vaccine tested in 60 volunteers shows immune response Subscription
An Ebola vaccine being developed by GlaxoSmithKline and the US National Institutes of Health is well tolerated and generates an immune response, according to initial testing of the vaccine in 60 healthy volunteers.
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Q&A: Getting life-saving vaccines to children in poor countries Subscription
Gavi, the Vaccine Alliance, brings together public and private sectors to deliver new and underused vaccines for children living in poor countries. Seth Berkley, its chief executive officer, discusses the current challenges to increase immunisation coverage in poor countries.
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Most popular features of 2014 from The Pharmaceutical Journal
Using visual representations of data to tell a story is proving popular, with infographic features taking first, second and third place in the top five features of 2014.
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Top 10 learning articles of 2014 from The Pharmaceutical Journal
Our response to the Ebola outbreak is a sign of how our learning content is changing to meet your needs.
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Human trials of ‘prime and boost’ Ebola vaccine underway Subscription
The University of Oxford has begun a phase I clinical trial of a preventive Ebola vaccine that uses a ‘prime and boost’ approach.
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What is a hospital ship?
The Royal Fleet Auxiliary Argus, a ship that has been helping with the Ebola crisis in west Africa, is equipped with a 100-bed medical complex, but it cannot be classified as a hospital ship. Roger Poole explains.
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Q&A: Ebola pioneer looks to the future of drug development Subscription
Microbiologist Peter Piot helped discover the Ebola virus in 1976. Now director and professor of global health at the London School of Hygiene and Tropical Medicine, he shares his thoughts on the current Ebola epidemic and describes some of the challenges in bringing new medicines for neglected diseases to market.
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Evidence still lacking for Ebola treatments, concludes European Medicines Agency Subscription
Lack of evidence for seven investigational drugs being developed for the treatment of Ebola means it is impossible to make conclusions about their safety or efficacy.
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Ebola clinical trial suspended after volunteers complain of joint pains Subscription
A phase I clinical trial of the fast-tracked Ebola vaccine VSV-ZEBOV has been halted in Switzerland because some trial participants developed mild joint pain.
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FIP guidance about the Ebola virus Subscription
The International Pharmaceutical Federation (FIP) has published a suite of resources about the Ebola virus, specifically for community pharmacists. All of the resources, including quick guidance, posters and a Microsoft Powerpoint presentation, are available from the FIP website.
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Ebola research gets a 280m euro boost from EU and drug industry Video Subscription
The European Union has pledged 280m euro to a research project to develop vaccines and diagnostic tests for Ebola.
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Johnson & Johnson accelerates Ebola vaccine push Subscription
Johnson & Johnson’s pharmaceuticals unit, Janssen, will invest US$200m in accelerating and expanding production of its Ebola vaccine.
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Not every problem is viral
We must not allow fears about Ebola and other viruses to obscure the threat of antimicrobial resistance, writes Eamonn McArdle.
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Fight against Ebola growing stronger in Liberia Subscription
Pharmacists in Liberia report that the fight against Ebola is gaining momentum with traditional leaders in rural villages implementing measures to stop transmission.
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Ebola update Subscription
The Department of Health has issued an update on the Ebola virus outbreak in West Africa, providing a reminder of the need to remain vigilant for cases imported to the UK. The update is available from the DH website.
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UK can expect a “handful” of Ebola cases, Hunt tells MPs Subscription
The UK is expected to have a “handful” of Ebola cases in the next three months, health secretary Jeremy Hunt told MPs.
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Finger snap silenced by Ebola
People in Liberia have been advised not to shake hands in the traditional manner because of fears that this may spread the Ebola virus, writes Roger Poole.
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Standing up to Ebola Subscription
Pharmacists may not be needed at the bedside in the present Ebola epidemic, but their experience in pharmaceutical logistics should be utilised.
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European Medicines Agency to review Ebola therapies Subscription
Experimental Ebola treatments are to be reviewed by the European Medicines Agency as part of the international response to the disease outbreak in West Africa.
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A visual guide to the Ebola virus epidemic Subscription
As the 2014 Ebola virus epidemic continues to escalate, we chart the latest epidemiological data alongside an insight into the pathology of Ebola virus disease and the biological processes being targeted by drug and vaccine developers.
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Ebola trials fast-tracked in Africa Subscription
Experimental drugs for Ebola are to be fast-tracked in clinical trials being set up in West African states that are fighting the epidemic.
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UK pharmacists asked to volunteer in Ebola outbreak
UK pharmacists have been urged to volunteer in the fight against Ebola in West Africa in an open letter from four of the most senior figures in UK healthcare.
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Ebola advice for NHS staff Subscription
The Department of Health and Public Health England have published a letter containing advice for healthcare professionals who want to volunteer to support those dealing with the outbreak of the Ebola virus in West Africa. The letter is available ...
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How pharmacists in Nigeria are helping to manage the Ebola outbreak
With a total of 90 representatives from Nigeria, Ghana and Cameroon at this year’s FIP congress in Thailand, Ebola was a recurrent theme.
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First UK volunteer receives experimental Ebola vaccine Subscription
An experimental Ebola vaccine has been tested in the first healthy UK volunteer, as part of a phase I clinical trial being conducted at the University of Oxford.
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World Health Organization expedites trials for potential Ebola vaccines Subscription
The World Health Organization has announced that two vaccines will be expedited to clinical trials and could be available as soon as November 2014 for priority use in healthcare workers.
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The Ebola outbreak
International health organizations are struggling to contain the biggest Ebola outbreak on record.
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Pharmacy can help fight against Ebola Subscription
As West African countries struggle to manage the current Ebola outbreak, more needs to be done internationally to improve the capabilities of the local pharmacy workforce.
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GSK to manufacture 10,000 Ebola vaccine doses as trials are fast-tracked
The Phase I trials will assess the safety of an experimental vaccine that is based on two formulations, with full results expected in 2015.
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Positive results in monkeys from first ZMapp trial to treat Ebola
ZMapp, an experimental combination of three monoclonal antibodies, has successfully cleared Ebola virus infection in monkeys, paving the way for human trials of the therapy.
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Ebola: what pharmacists need to know Subscription
Pharmacists are ideally placed to help educate the public during the current outbreak of Ebola virus disease.
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Tens of thousands need access to Ebola treatment or prophylaxis
Up to 30,000 people would have so far required treatment or prophylaxis in the current Ebola outbreak in West Africa, according to a “crude” analysis.
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Initiative sees pharmacists offer Ebola advice in Liberian drug stores
Pharmacists and pharmacy students in Liberia are to visit drug stores and pharmacies to give staff advice about preventing the spread of the Ebola virus.
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Make investigational Ebola drugs available, say ethicists
Drugs in development can be used for the treatment of Ebola, an international panel of ethics experts has recommended to the World Health Organization.
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Medicines supply chain ‘overwhelmed’ by Ebola crisis
Pharmacists working in West Africa have spoken about the overwhelming scale of the challenges they have faced in Liberia in the battle against the Ebola virus.
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WHO to debate ethical issues surrounding experimental Ebola drugs
The main topics of discussion will be who should be first in line to receive the treatment and whether the drugs are safe for human consumption.
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WHO launches $100m plan to tackle Ebola
The World Health Organization and African leaders meet to discuss plans to bring the ’unprecedented’ Ebola outbreak under control in West Africa.
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Public Health England warns of Ebola virus
Healthcare professionals should look out for symptoms of Ebola virus infection in patients who have travelled to Guinea, Liberia or Sierra Leone in the past 21 days.
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Ebola vaccine hope Subscription
Researchers have successfully immunised mice against the deadly Ebola virus in the hope of developing a human vaccine. They used virus-like particles made of the Ebola virus’s two coat proteins. After exposure to the real virus, all of the immunised mice ...
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