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The precision medicine approach to cancer therapy: part 1 — solid tumours Subscription
An overview of the anticancer agents that have been approved for use in the UK as part of a precision medicine approach for solid tumours, along with information relating to the relevant biomarkers and biomarker assays currently available.
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Role of dual and triple fixed-dose combination inhalers in the treatment of chronic obstructive pulmonary disease Subscription
A review of the current evidence, including the safety and efficacy of dual and triple-combination inhalers for the treatment of stable COPD, and their place in therapy.
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Simulation-based training: applications in clinical pharmacy Subscription
With the evolving role of pharmacists and the growing complexity of healthcare, there is a need for interventions and innovations to enhance both individual task and team performance. Simulation-based training is an educational platform with potential in this area. This article outlines its applications in pharmacy and how it can support the skill acquisition and development of pharmacists.
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Risk factors for mortality, hospitalisation and imprisonment in substance misuse patients Subscription
Pharmacists should be aware of the mortality rates and adverse outcomes, including hospitalisation and imprisonment, that are rife in illicit drug users and patients on opioid substitution therapy, in order to optimise patient safety and reduce adverse outcomes.
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Pharmacy’s role in antimicrobial resistance and stewardship Subscription
This article summarises the evidence supporting the role of pharmacists and pharmacy teams in antimicrobial stewardship and outlines the impact of their activities.
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Community pharmacists' contribution to public health: assessing the global evidence base
In the UK, community pharmacies are more accessible to the general population than general practices. Therefore, government white papers and briefing documents from pharmacy professional bodies have advocated the expansion of the role of community pharmacists, particularly in relation to the provision of services that contribute to disease prevention and health improvement. It is unknown whether the same evidence exists globally for the expansion of these roles. This article attempts ...
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Glucose-lowering drugs and cardiovascular risk: how recent outcome trials have informed practice
Although large clinical trials with glucose-lowering drugs have consistently shown beneficial reductions in microvascular complications, their effects on macrovascular complications have been controversial. Interpreting these trials is complicated by substantial differences in their design, the populations studied and data analysis. This article examines how the trials have evolved and how they impact the use of glucose-lowering agents in the routine care of patients with type ...
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Optimising the health and wellbeing of older people living with HIV in the United Kingdom Subscription
Care for people with HIV has improved, meaning that more people are living with HIV into older age with normal life expectancy. Therefore, there are various challenges and opportunities facing healthcare professionals when providing care to this changing demographic.
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Treatments for neuropathic pain
Neuropathic pain is a common condition characterised by subjective negative and positive symptoms that range from numbness to debilitating pain.
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Pharmacological treatment options for fibromyalgia Subscription
Fibromyalgia is a high-impact and prevalent condition. Its clinical features include widespread pain and tenderness — often associated with high levels of poor-quality sleep, fatigue and cognitive dysfunction. The mechanism leading to fibromyalgia development is associated with a change in the sensitivity of the pain-related nervous system, as well as other sensory systems. In turn, emotional distress plays a facilitatory role in this process. Non-pharmacological management focuses ...
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