Issue : CP June 2017 online
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Chronic open-angle glaucoma: case study Subscription
Understand how to advise on chronic-open angle glaucoma, a condition in which intraocular pressure can permanently damage the optic nerve and nerve fibre, leading to blindness if left untreated.
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Antiviral treatment improves outcomes in patients with advanced cirrhosis Subscription
Hepatitis C drug shown to reduce the need for transplant and lower mortality rate in patients with advanced liver disease.
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Effects of ADHD drug on the brain are reversible, study suggests Subscription
Even high doses over an extended treatment period were not detectable in brain regions after a month’s abstinence, according to animal study.
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Leukaemia drug stems allergen response in exploratory study Subscription
The tyrosine kinase inhibitor ibrutinib can help to block allergic reactions and prevent anaphylaxis, a study finds.
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‘Liquid biopsy’ guides PARP inhibitor treatment of prostate cancer Subscription
Analysis of circulating free tumour DNA in blood shows how well cancer therapy is working and can inform further treatment.
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Metformin may have cardiovascular benefits in patients with type 1 diabetes Subscription
Guidelines recommend off-label use of metformin in type 1 diabetes to reduce insulin dosages and improve glycaemic control. However, it is not known whether it has any cardiovascular benefits.
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Experimental cholesterol drug failed to prevent cardiovascular events Subscription
Phase III trial halted early as treatment did not reduce rate of vascular events in patients with high-risk disease.
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Penicillin allergy often inaccurately recorded by healthcare professionals Subscription
Researchers find that only one-third of medical records accurately reflected patients’ reported allergic reactions to penicillin.
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Lack of robust post-approval studies under FDA system Subscription
Review of drugs approved on the basis of limited evidence concludes that stricter rules are needed for post-approval studies.
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Blood sugar self-monitoring in non-insulin treated type 2 diabetes doesn’t improve control Subscription
It has been debated whether self-monitoring blood glucose levels has any value in improving glycaemic control for patients with type 2 diabetes not requiring insulin.
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Non-selective beta-blockers increase fall risk in older adults Subscription
The association between beta-blockers and falls in patients aged 55 years and over may be related to the type prescribed, data analysis finds.
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Protein can assess and predict progression of Huntington’s disease Subscription
Researchers identify biomarker that offers a means of predicting and tracking neuronal damage in patients with Huntington’s disease.
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SGLT2 inhibitors linked to increased risk of diabetic ketoacidosis Subscription
In a study comparing treatments for type 2 diabetes, SGLT2 inhibitors show double the risk of ketoacidosis versus gliptins.
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Taking vitamin D during pregnancy boosts neonatal immune system Subscription
Analysis of the umbilical cords of newborns suggests that maternal vitamin D supplementation may help to reduce the risk of allergic conditions in early life.
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Paediatric epilepsy drug response linked to common genetic variants Subscription
Recent research has shown that patients with childhood absence epilepsy, the most common form of paediatric epilepsy, have highly variable responses to antiepileptic medications.
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Treatment-resistant epilepsy in children: new hope from cannabidiol Subscription
A large clinical trial conducted on a drug derived from cannabis has demonstrated reduction of convulsive seizures experienced by children with a severe form of epilepsy by nearly 50%[1]. The results, ...
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Excellence should be the norm Subscription
22 May 2017: Aileen Bryson, acting director of RPS Scotland, wrote an opinion piece for Scotland on Sunday outlining how pharmacists could contribute to relieving the pressure on GP services. In her piece, Bryson said: “There are many areas of excellence in practice and innovation across Scotland which we must strive to make the norm in both secondary and primary care to improve patient safety, patient care and the patient journey.”
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