Issue : CP June 2017 online
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Chronic open-angle glaucoma: case study Subscription
Understand how to advise on chronic-open angle glaucoma, a condition in which intraocular pressure can permanently damage the optic nerve and nerve fibre, leading to blindness if left untreated.
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Antiviral treatment improves outcomes in patients with advanced cirrhosis Subscription
Hepatitis C drug shown to reduce the need for transplant and lower mortality rate in patients with advanced liver disease.
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Effects of ADHD drug on the brain are reversible, study suggests Subscription
Even high doses over an extended treatment period were not detectable in brain regions after a month’s abstinence, according to animal study.
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Leukaemia drug stems allergen response in exploratory study Subscription
The tyrosine kinase inhibitor ibrutinib can help to block allergic reactions and prevent anaphylaxis, a study finds.
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‘Liquid biopsy’ guides PARP inhibitor treatment of prostate cancer Subscription
Analysis of circulating free tumour DNA in blood shows how well cancer therapy is working and can inform further treatment.
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Metformin may have cardiovascular benefits in patients with type 1 diabetes Subscription
Guidelines recommend off-label use of metformin in type 1 diabetes to reduce insulin dosages and improve glycaemic control. However, it is not known whether it has any cardiovascular benefits.
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Experimental cholesterol drug failed to prevent cardiovascular events Subscription
Phase III trial halted early as treatment did not reduce rate of vascular events in patients with high-risk disease.
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Penicillin allergy often inaccurately recorded by healthcare professionals Subscription
Researchers find that only one-third of medical records accurately reflected patients’ reported allergic reactions to penicillin.
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Lack of robust post-approval studies under FDA system Subscription
Review of drugs approved on the basis of limited evidence concludes that stricter rules are needed for post-approval studies.
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Blood sugar self-monitoring in non-insulin treated type 2 diabetes doesn’t improve control Subscription
It has been debated whether self-monitoring blood glucose levels has any value in improving glycaemic control for patients with type 2 diabetes not requiring insulin.
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