Issue : Clinical Pharmacist, June 2016, Vol 8, No 6
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Chronic obstructive pulmonary disease: clinical phenotypes and implications for management Subscription
Phenotyping patients with chronic obsructive pulmonary disease allows their separation into distinct categories that differentiate their prognosis and response to treatment, producing clinically meaningful outcomes.
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How polypharmacy has become a medical burden worldwide Subscription
More patients than ever are taking a multitude of medicines and supplements, but this can cause more harm than good.
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Improving long-term adjuvant anti-oestrogenic therapy for breast cancer Subscription
Long-term (five years) adjuvant tamoxifen treatment for oestrogen receptor-positive, or ER-positive, breast cancer post-surgery is recognised as a major advance in healthcare. Clinical trials comparing standard and extended tamoxifen therapy found a major decrease in mortality occurred in the ten years following a decade of adjuvant therapy. Studies in premenopausal breast cancer patients showed that ovarian function suppression (OFS) plus an aromatase inhibitor (AI), ...
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Reducing medication discrepancies in elderly patients Subscription
Older patients are more susceptible to harm from polypharmacy and transfer between care settings can result in medication discrepancies. To address this issue Birmingham South Central Clinical Commissioning Group (CCG), in partnership with NHS Midlands and Lancashire Commissioning Support Unit, conducted a pilot project, where prescribing support via a pharmacist and pharmacy technician were offered to GPs through conducting post-discharge medication reviews in patients who were aged ...
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No guarantee of quality with unlicensed vitamin D products Subscription
Colin Michie’s article on the risks of vitamin D self supplementation makes many useful points, including the risks associated with excess vitamin D (Clinical Pharmacist, 2016;8:131). But there is one major issue that was not highlighted: the vast majority of vitamin D products sold through pharmacies and elsewhere ...
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A downside to electronic prescribing Subscription
I write regarding your excellent review in the May edition of Clinical Pharmacist (2016;8:144).
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Early aspirin use after transient ischaemic attack cuts severe stroke risk by 90% Subscription
Large analysis of data shows taking aspirin within two weeks of transient ischaemic attack or stroke cuts risk of secondary stroke by over 90%.
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Umbilical cords longer in babies exposed to SSRIs Subscription
Data show babies born to women who used SSRIs also had lower Apgar scores and were more likely to be admitted to neonatal intensive care.
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Study shows how proton pump inhibitors damage blood vessel cells Subscription
New research into harmful effects of PPIs suggests that the drugs impair vascular cells.
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Ketamine metabolite relieves depression with fewer side effects Subscription
Study findings could inform the development of more effective and safe treatments for depression.
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