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Issue : PJ July 2015 online

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  • The use of antipsychotic medication by adolescents and young people aged between 13 and 24 has risen in the US. Depression was the most common diagnosis for 19 to 24 year olds who received antipsychotics

    Rise of antipsychotic drug use in 13–24 year olds in United States Subscription

    3 JUL 2015 13:34

    The use of antipsychotic drugs by young people aged 13–24 years has risen in the United States between 2006 and 2010 but has fallen in those aged between 1–12 years of age, according to research published in JAMA Psychiatry. 

  • Arrhythmia with Moviprep Subscription

    29 JUL 2015 10:18

    Arrhythmia has been added as an adverse event with unknown frequency to the summary of product characteristics (SPC) for Moviprep (macrogol, sodium sulfate anhydrous, sodium chloride, potassium chloride, ascorbic acid, sodium ascorbate; Norgine). Additionally, the SPC now states that two litres of Moviprep can be taken in the morning of a clinical procedure.

  • AWMSG medicines approvals Subscription

    27 JUL 2015 9:53

    The following medicines have been approved for use in NHS Wales by the All Wales Medicines Strategy Group (AWMSG): Darunavir, in combination with other antiretrovirals, for treating human immunodeficiency virus-1 infection in children aged at least three years and weighing 15kg and over; peginterferon beta-1a for treating adults with relapsing-remitting multiple sclerosis; regorafenib for treating adults with unresectable or metastatic gastrointestinal stromal tumours who progressed ...

  • Disipal tablets discontinued Subscription

    29 JUL 2015 11:51

    Astellas is discontinuing Disipal tablets (orphenadrine hydrochloride) 50mg from 1 December 2015 because of manufacturing issues. Disipal can be ordered until 30 November 2015.

  • Drug alert for Xenidate XL Subscription

    10 JUL 2015 12:43

    The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a class 4 drug alert for a small number of packs from a specific batch of Xenidate XL (methylphenidate hydrochloride; Mylan UK) prolonged-release tablets 36mg. Further information ...

  • Extended indication for Relistor Subscription

    29 JUL 2015 9:01

    Relistor (methylnaltrexone bromide; TMC Pharma Services) is now indicated for opioid-induced constipation when response to laxative therapy has not been sufficient in adults aged 18 years and older. Further changes to the summary of product characteristics reflect this license extension.

  • Researchers have elucidated the reasons why an HIV-1 vaccine, RV144, led to a mixed response in terms of HIV-1 infection risk. In the image, micrograph of HIV-1 budding (green) from cultured lymphocyte

    Genetics may play a role in efficacy of HIV vaccine Subscription

    21 JUL 2015 10:22

    Variation in individuals immune response genes could explain why the vaccine worked in some but not others.

  • The pharmaceutical industry has vowed to continue its supply of medicines to Greece, but there are other potential problems if the country leaves the eurozone. In the image, protesters march down the streets of Athens

    Greek debt crisis will not affect supply of medicines, pharmaceutical companies say Subscription

    2 JUL 2015 12:57 By Elizabeth Sukkar

    Pharmaceutical companies will provide a constant supply of medicines to the people of Greece through the financial crisis, says the Hellenic Association of Pharmaceutical Companies.

  • A judicial review against the Health Research Authority, challenging the steps it took to monitor the registration of clinical trials, has been upheld by High Court judge, Justice Robert Jay (pictured)

    High Court rules against Health Research Authority in clinical trial transparency case Subscription

    30 JUL 2015 15:45

    A judicial review against the Health Research Authority, challenging the steps it took to monitor the registration of clinical trials, has been upheld by a High Court judge.

  • Worldwide an estimated 246 million people - or slightly more than 5% of those aged 15 to 64 years - used an illicit drug in 2013, up by three million over the previous year, according to the World Drug Report, 2015

    Illicit drug users are on the rise, finds UN report Subscription

    10 JUL 2015 15:17

    Worldwide an estimated 246 million people used an illicit drug in 2013, a rise of three million over the previous year, says a report by the UN Office on Drugs and Crime.

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