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Issue : PJ November 2015 online

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  • Additional filter size for Kadcyla Subscription

    17 NOV 2015 12:18

    The summary of product characteristics for Kadcyla (trastuzumab emtansine; Roche) has been revised to include recommendations on an additional filter size of 0.2 micron for in-line filtration during infusion using sodium chloride 0.9% as a solvent.

  • Researchers report that disulfiram, molecular structure pictured), a drug used to treat alcoholism, can reactivate latent HIV. The findings represent a step towards eliminating latent HIV

    Alcoholism drug could help eliminate dormant HIV Subscription

    27 NOV 2015 14:28

    Disulfiram treatment can reactivate latent HIV, which could help eliminate the cells harbouring the virus, report finds.

  • Researchers are developing antibodies armed with antibiotics that can target and kill the bacteria, such as Staphylococcus aureus, (micrograph pictured) concealed in the white blood cells

    Antibody-antibiotic conjugates fight S. aureus infection Subscription

    5 NOV 2015 16:07 By Suzanne Elvidge

    Antibodies armed with antibiotics that can target and kill Staphylococcus aureus concealed in white blood cells are being developed by researchers at US company Genentech, according to a paper published in Nature on 4 November 2015.

  • Findings show that andexanet could provide a rapid antidote to factor Xa inhibitors (molecular structure pictured) for patients who experience bleeding or need emergency surgery

    Antidote to new oral anticoagulants proves effective Subscription

    20 NOV 2015 16:38

    Anticoagulant effects of factor Xa inhibitors can be reversed by inactive recombinant factor Xa protein, andexanet, study shows.

  • Antimicrobial resistance guidance from FIP Subscription

    27 NOV 2015 14:07

    The International Pharmaceutical Federation (FIP) has published a resource to support pharmacists in implementing policies to combat antimicrobial resistance. The document is available from the FIP website.

  • Antimicrobial resistance strategy for veterinary medicines Subscription

    20 NOV 2015 16:05

    The European Medicines Agency (EMA) has released for public consultation a new strategy on antimicrobial resistance addressing medicinal products for veterinary use. The consultation documents can be accessed on the

  • AWMSG November medicines approvals Subscription

    20 NOV 2015 16:22

    The following medicines have been approved for use in NHS Wales by the All Wales Medicines Strategy Group (AWMSG): Xultophy (insulin degludec and liraglutide) for use with oral antidiabetic drugs to treat adults with type 2 diabetes — it can only be used when oral treatments combined with basal insulin do not provide adequate glycaemic control; Fomicyt (fosfomycin) to treat acute osteomyelitis, complicated urinary tract infections, nosocomial lower respiratory tract infections or bacterial ...

  • Treatment with beta-lactam antibiotics could exacerbate methicillin-resistant Staphylococcus aureus (MRSA, pictured) skin infections, according to pre-clinical research published in Cell Host & Microbe

    Beta-lactam antibiotics can make MRSA infection worse Subscription

    12 NOV 2015 16:27 By George Winter

    Treatment with beta-lactam antibiotics could exacerbate MRSA skin infections, according to pre-clinical research. 

  • Research shows a blood test could predict which antidepressant will work for each patient. In the image, blood from tests ready to be analysed

    Blood test could show whether an antidepressant is effective, research suggests Subscription

    2 DEC 2015 9:52 By Bea Perks

    Psychiatrists could be on the way to developing a test that predicts which patients with depression will benefit from which antidepressant.

  • cp call for paper

    Call for papers: make your contribution to the new Clinical Pharmacist

    19 NOV 2015 16:56

    We are accepting the following types of article for peer review

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