Issue : PJ November 2015 online
Fostair NEXhaler indicated for COPD Subscription
Fostair NEXhaler (beclometasone diproprionate, formoterol fumarate dihydrate; Chiesi) is now indicated for patients with chronic obstructive pulmonary disease. Further changes to the summary of product characteristics reflect this addition.
Draft guidance for recurrent ovarian cancer Subscription
The National Institute for Health and Care Excellence (NICE) has published draft guidance that covers five drugs — paclitaxel, pegylated liposomal doxorubicin hydrochloride (PLDH), topotecan, trabectedin and gemcitabine — for treating recurrent ovarian cancer. The guidance recommends paclitaxel and PLDH for treating recurrent ovarian cancer but proposes not recommending gemcitabine, topotecan and trabectedin for treating the first recurrence of platinum-sensitive ovarian cancer (where ...
Edurant indication extension for adolescents Subscription
The summary of product characteristics for Edurant (rilpivirine; Janssen-Cilag) now states that the drug can be taken by adolescents of 12 years and above, as well as adults.
Hospitals have variable stock levels of antidotes Subscription
Hospital stock control of antidotes to treat poisoned patients have improved but there is still “significant” differences between NHS trusts.
Intestinal obstruction with Xifaxanta Subscription
Intestinal obstruction is now listed as an adverse reaction in the summary of product characteristics for Xifaxanta (rifaximin; Norgine). Additionally, the drug may reduce the effectiveness of oral estrogenic contraceptives if taken concomitantly. Caution should also be exercised when rifaximin is given concomitantly with a P-glycoprotein inhibitor, such as ciclosporin.
Contraindications with Aldomet Subscription
Aldomet (methyldopa; Aspen) is now contraindicated with a catecholamine-secreting tumour, such as pheochromocytoma or paraganglioma, and with porphyria. Additionally, the summary of product characteristics now states that the use of the drug in women who are pregnant or may become pregnant, or in breast-feeding mothers, requires that the anticipated benefits are weighed against potential risks.
How we refurbished a famous London pharmacy Subscription
John Bell & Croyden pharmacy, which first opened over 200 years ago and holds the Royal warrant, has just had a £4m makeover.
Side effects with Eviplera Subscription
The summary of product characteristics for Eviplera (emtricitabine, rilpivirine, tenofovir disoproxil; Gilead) now states that Eviplera must be discontinued as soon as serious skin and/or mucosal reactions are observed, and appropriate therapy should be initiated.
Alcoholism drug could help eliminate dormant HIV Subscription
Disulfiram treatment can reactivate latent HIV, which could help eliminate the cells harbouring the virus, report finds.
Contraindication for Diflucan Subscription
Concomitant administration of amiodarone is now contraindicated with Diflucan (fluconazole; Pfizer), according to the updated summary of product characteristics.