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Issue : PJ November 2015 online

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  • Fostair NEXhaler indicated for COPD Subscription

    30 NOV 2015 13:33

    Fostair NEXhaler (beclometasone diproprionate, formoterol fumarate dihydrate; Chiesi) is now indicated for patients with chronic obstructive pulmonary disease. Further changes to the summary of product characteristics reflect this addition.

  • Draft guidance for recurrent ovarian cancer Subscription

    30 NOV 2015 13:24

    The National Institute for Health and Care Excellence (NICE) has published draft guidance that covers five drugs — paclitaxel, pegylated liposomal doxorubicin hydrochloride (PLDH), topotecan, trabectedin and gemcitabine — for treating recurrent ovarian cancer. The guidance recommends paclitaxel and PLDH for treating recurrent ovarian cancer but proposes not recommending gemcitabine, topotecan and trabectedin for treating the first recurrence of platinum-sensitive ovarian cancer (where ...

  • Edurant indication extension for adolescents Subscription

    30 NOV 2015 13:14

    The summary of product characteristics for Edurant (rilpivirine; Janssen-Cilag) now states that the drug can be taken by adolescents of 12 years and above, as well as adults. 

  • Hospital stock control of antidotes to treat poisoned patients have improved but there is still “significant” differences between NHS trusts, according to research published. In the image, stock of medicines in a hospital pharmacy

    Hospitals have variable stock levels of antidotes Subscription

    27 NOV 2015 16:58
    Comments (1)

    Hospital stock control of antidotes to treat poisoned patients have improved but there is still “significant” differences between NHS trusts.

  • Intestinal obstruction with Xifaxanta Subscription

    27 NOV 2015 15:08

    Intestinal obstruction is now listed as an adverse reaction in the summary of product characteristics for Xifaxanta (rifaximin; Norgine). Additionally, the drug may reduce the effectiveness of oral estrogenic contraceptives if taken concomitantly. Caution should also be exercised when rifaximin is given concomitantly with a P-glycoprotein inhibitor, such as ciclosporin.

  • Contraindications with Aldomet Subscription

    27 NOV 2015 14:53

    Aldomet (methyldopa; Aspen) is now contraindicated with a catecholamine-secreting tumour, such as pheochromocytoma or paraganglioma, and with porphyria. Additionally, the summary of product characteristics now states that the use of the drug in women who are pregnant or may become pregnant, or in breast-feeding mothers, requires that the anticipated benefits are weighed against potential risks.

  • Cormac Tobin (pictured), managing director of Celesio UK, which owns John Bell & Croyden, describes the history of the pharmacy and explains what changes have been made

    How we refurbished a famous London pharmacy Subscription

    27 NOV 2015 14:43 By Cormac Tobin

    John Bell & Croyden pharmacy, which first opened over 200 years ago and holds the Royal warrant, has just had a £4m makeover.

  • Side effects with Eviplera Subscription

    27 NOV 2015 14:30

    The summary of product characteristics for Eviplera (emtricitabine, rilpivirine, tenofovir disoproxil; Gilead) now states that Eviplera must be discontinued as soon as serious skin and/or mucosal reactions are observed, and appropriate therapy should be initiated. 

  • Researchers report that disulfiram, molecular structure pictured), a drug used to treat alcoholism, can reactivate latent HIV. The findings represent a step towards eliminating latent HIV

    Alcoholism drug could help eliminate dormant HIV Subscription

    27 NOV 2015 14:28

    Disulfiram treatment can reactivate latent HIV, which could help eliminate the cells harbouring the virus, report finds.

  • Contraindication for Diflucan Subscription

    27 NOV 2015 14:22

    Concomitant administration of amiodarone is now contraindicated with Diflucan (fluconazole; Pfizer), according to the updated summary of product characteristics.

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