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Issue : PJ November 2015 online

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  • Study shows insulin pump (pictured) use in England and Wales was 30% of that in other countries. Researchers say the lower level of pump use in England/Wales may be due to relatively restrictive national guidelines on their use in paediatrics

    England and Wales lag behind other countries for paediatric insulin pump use Subscription

    18 NOV 2015 16:31

    International study shows insulin pump use in England and Wales was 30% of that in other countries.

  • A team from the Massachusetts General Hospital (MGH) in Boston observed medication errors and adverse drug events during 277 randomly selected operations over an eight-month period. In the image, main entrance of MGH

    Perioperative medication error rates higher than expected Subscription

    18 NOV 2015 15:59

    A study conducted at Massachusetts General Hospital in Boston found that almost half of 277 randomly selected operations involved a medication error or adverse drug event.

  • Researchers say that ‘liquid biopsy’ could potentially be used to select patients  with advance prostate cancer for alternative treatments, but this would need validation in a randomised trial. In the image, light micrograph of prostate cancer cells

    Liquid biopsy predicts treatment resistance in advanced prostate cancer Subscription

    18 NOV 2015 14:46

    Patients with prostate cancer could be selected for alternative treatments using liquid biopsy, researchers say.

  • Fewer antibiotic prescriptions are issued for acute respiratory infections when doctors make decisions jointly with patients, according to a review of clinical trials. In the image, a doctor speaks with a patient

    Fewer antibiotics prescribed when doctors share decision with patients Subscription

    17 NOV 2015 15:51 By Bea Perks

    Fewer antibiotic prescriptions are issued for acute respiratory infections when doctors share decision making with patients, according to a review published by the Cochrane Library on 12 November 2015.

  • GPs and community pharmacists have been told not allow their financial interests to influence the advice they give patients. It comes as community pharmacists are able to offer flu vaccination. In the image, a woman receives a flu vaccination

    Patients should be free to choose where to access services, regulators say Subscription

    17 NOV 2015 14:18 By Debbie Andalo

    GPs and community pharmacists should not allow financial interests to influence the advice they give patients about where to access services, their respective regulators have told them.

  • New requirements for controlled drugs Subscription

    17 NOV 2015 13:45

    The Home Office has highlighted two changes affecting controlled drugs. First, from 30 November 2015, amendments to the Misuse of Drugs Regulations 2001 will make the use of an approved form for the requisitioning of Schedule 2 and 3 Controlled Drugs in the community mandatory. This applies to both requisitions for human and for veterinary use.

  • Additional filter size for Kadcyla Subscription

    17 NOV 2015 12:18

    The summary of product characteristics for Kadcyla (trastuzumab emtansine; Roche) has been revised to include recommendations on an additional filter size of 0.2 micron for in-line filtration during infusion using sodium chloride 0.9% as a solvent.

  • Contraindications with Ex-lax Senna Pills Subscription

    17 NOV 2015 12:07

    The summary of product characteristics (SPC) for Ex-lax Senna Pills (sennoside; Novartis) now states that the medicine is contradicted with irritation of the gastrointestinal tract, abdominal pain of unknown origin, severe dehydration states, especially hypokalaemia, and in children aged under 12 years. Patients taking cardiac glycosides, antiarrhythmic medicinal products, medicinal products inducing QT-prolongation, diuretics, adrenocorticosteroids or liquorice root, have to consult ...

  • November 2015: SMC decisions Subscription

    16 NOV 2015 16:57

    The Scottish Medicines Consortium has accepted the following medicines for use in NHS Scotland: atazanavir and cobicistat (Evotaz; Bristol-Myers Squibb); edoxaban (Lixiana; Daiichi Sankyo), for two separate indications; pembrolizumab (Keytruda; Merck Sharp and Dohme), as monotherapy for the treatment of advanced (unresectable or metastatic) melanoma in adults previously untreated with ipilimumab; tiotropium/olodaterol (Spiolto Respimat; Boehringer Ingelheim); and triamcinolone hexacetonide ...

  • Reduced efficacy of benzodiazepines with Xenical Subscription

    16 NOV 2015 16:28

    The summary of product characteristics for Xenical (orlistat; Roche) now states that there are some case reports of reduced efficacy of benzodiazepines coincidental to the initiation of orlistat treatment in previously well controlled patients. Therefore, orlistat treatment should only be initiated after careful consideration of the possible impact in these patients.

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