Category list : Animal experimentation
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‘Neurostatin’ prevents Alzheimer's-related amyloid formation Subscription
Roundworm study shows bexarotene could inhibit early step of amyloid-beta aggregation.
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2014: The Pharmaceutical Journal's news in review Subscription
Looking back at some of the biggest news stories from the past year.
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A new structural model for enamel
Researchers in Illinois have found that rodent enamel is similar in structure to human enamel. This model could help to improve current fluoride treatment and dental health in humans.
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Acne drug boosts pancreatic cancer chemotherapy in mice Subscription
Combination of retinoid tretinoin and gemcitabine chemotherapy reduces cancer cell proliferation and invasiveness.
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Alzheimer’s inflammation targeted with period pain NSAID Subscription
Flufenamic acid and mefenamic acid successfully reduced inflammation and memory deficits in rodent model of Alzheimer’s disease.
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Alzheimer's drug development could be aided by multiple mouse-model validation Subscription
Research suggests that GPR3, a receptor implicated in Alzheimer’s disease pathology, mediates disease progression and is a potential target for drug development.
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Antibiotic gel crosses eardrum to treat middle ear infections
A one-dose application of an antibiotic gel into the ear could make it easier to treat middle ear infections in children, say US researchers.
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Antibody-antibiotic conjugates fight S. aureus infection Subscription
Antibodies armed with antibiotics that can target and kill Staphylococcus aureus concealed in white blood cells are being developed by researchers at US company Genentech, according to a paper published in Nature on 4 November 2015.
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Anti-cholesterol vaccine shows promise Subscription
A vaccine that targets PCSK9 could be a cost effective approach to lowering cholesterol.
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Antidiabetic drug could combat cancer drug resistance Subscription
Adding an antidiabetic drug to treatment with antiangiogenic multi-tyrosine kinase inhibitors resulted in a reduction in tumour growth.
