Category list : Animal experimentation
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Widely used NSAID treats Alzheimer’s disease in mice
The anti-inflammatory drug mefenamic acid can reverse memory loss and brain inflammation in a mouse model of Alzheimer’s disease, a study shows.
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Enhanced flu vaccine still doesn’t protect obese mice Subscription
Researchers discovered that influenza vaccine adjuvants did not increase response in obese mice.
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Novel antibiotic isolated from human nose
A new antibiotic that can kill MRSAfree has been discovered in the human nose by researchers at the University of Tübingen in Germany.
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Research unravels how brain changes in Alzheimer’s linked to diabetes Subscription
An enzyme closely linked to brain changes in Alzheimer’s disease also seems to have a role in glucose control, according to a study published in Diabetologia.
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Antidiabetic drug could combat cancer drug resistance Subscription
Adding an antidiabetic drug to treatment with antiangiogenic multi-tyrosine kinase inhibitors resulted in a reduction in tumour growth.
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Coenzyme protects against diabetes complications in mice Subscription
Mice with diabetes given nicotinamide riboside, an NAD+ precursor, had reduced weight gain, improved glycaemic control and reduced liver damage, compared with controls.
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Acne drug boosts pancreatic cancer chemotherapy in mice Subscription
Combination of retinoid tretinoin and gemcitabine chemotherapy reduces cancer cell proliferation and invasiveness.
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Seizure disorder suppressed by aromatase inhibitors in rats Subscription
Letrozole and fadrozole significantly reduced seizure activity in rat model of status epilepticus.
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Ketamine metabolite relieves depression with fewer side effects Subscription
Study findings could inform the development of more effective and safe treatments for depression.
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Narrow spectrum antibiotic leaves gut microbiome intact in mice Subscription
Pathogen-selective antibiotics could minimise the impact of treatment on the gut microbiome, study finds.
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