Category list : Antifungal agents

Pharmacists should make themselves familiar with the Antifungal Drug Interactions Database Subscription

In this time of growing antimicrobial resistance, we do not have unlimited ways to effectively treat a systemic infection. We must be antimicrobial stewards and use antimicrobials responsibly to preserve their effectiveness[1]. This applies to antifungals too — not just antibiotics

Aspergillosis: causes, types and treatment Subscription

Aspergillus-related disease is rare, but results in high mortality rates. The limited treatment options and emerging antifungal drug resistance mean that accurate diagnosis and management is paramount.

How to improve antifungal stewardship Subscription

Selecting appropriate antifungal therapies and performing ongoing reviews of these therapies can help support antifungal stewardship efforts and help reduce antifungal resistance.

Thrush: detection and management in community pharmacy

Pharmacists can provide treatment and advice for this common yeast infection.

Canesten range updated Subscription

Bayer is updating its range of Canesten products. There will be changes to the naming and packaging, with the updated products being introduced from July 2015 until early 2016. The active ingredients and product composition will remain the same.

Caneston Bifonazole interaction with warfarin Subscription

The summary of product characteristics for Canesten Bifonazole Once Daily 1% w/w Cream (Bayer) now warns of a potential interaction with warfarin. Limited data suggests that an interaction between topical bifonazole and warfarin may be possible, leading to increases in INR [international normalised ratio]. If bifonazole is used in a patient on warfarin therapy they should be appropriately monitored. Closer monitoring may be ...

FDA grants priority approval for new antifungal Subscription

Isavuconazonium sulfate, an antifungal developed by Astellas, has been given priority approval by the US Food and Drug Administration to treat serious infections.

Antifungal agents interactions app and databases Subscription

The Fungal Infection Trust and the National Aspergillosis Centre have developed a freely available online resource and app for iPhone, iPad and Android devices, which displays potential interactions between antifungal agents and other medicines. The collaboration supported the development of two databases, one for patients and

Noxafil now available Subscription

Noxafil (posaconazole) is now available from Merck Sharp & Dohme. Net price: Concentrate for solution for infusion 300mg, 1 x glass vial, £211; oral suspension 40mg/ml, 1 x 105ml bottle, £491.20; gastro-resistant tablets 100mg, 24 x tablets, £596.96, 96 x tablets, £2,387.85.

Pevaryl cream is not recommended during pregnancy Subscription

Pevaryl (econazole nitrate; Janssen-Cilag) topical cream 1% is not recommended during pregnancy, because there is low systemic absorption of econazole, according to the updated summary of product characteristics. 

Micafungin well tolerated by leukaemia patients Subscription

Micafungin is as effective at preventing fungal infections in leukaemia patients but better tolerated than older formulations of posaconazole, interim results from a study suggested.

Experimental antifungal drug causes fewer side effects than voriconazole Subscription

A new experimental anti-fungal treatment is no less effective than its predecessor, but exposes patients to fewer side effects, a study has found.

Over-the-counter treatments for athlete's foot Subscription

This fungal skin infection is estimated to affect more than 15% of the world’s population. Make sure your pharmacy team knows how to advise patients in managing this common condition.

Novel plastic-derived antifungal shows promise in infections Subscription

Candida albicans Source: Sebastian Kaulitzki/Dreamstime.com Candida albicans infections could be treated with the a new anti-fungal in the future

Superseding antifungal creams and pessaries — the story of fluconazole Subscription

Continuing with our landmark drugs series, Jenny Bryan looks how a change of fortune led fluconazole to join the elite ranks of blockbuster drugs 

Asthma and antifungals

Patients with difficult-to-treat, severe asthma and who have allergic sensitivity to at least one of seven common fungi may benefit from an oral antifungal.In a small study (n=58), patients who took itraconazole 200mg bd scored higher in a quality of life questionnaire than those on placebo.

Oral antifungals may benefit severe asthma patients

Patients who suffer from severe asthma may benefit from oral antifungal therapy, according to researchers at the University of Manchester.

New antifungal micafungin among drugs accepted by SMC

Antifungal micafungin launched

A new drug for the treatment of serious fungal infections has been launched by Astellas Pharma.

Drug interactions that can occur with azole antifungals Subscription

Karen Baxter, editor Alison Marshall, staff editor Jennifer Sharp, staff editor Stockley's Drug Interactions

Treatment of bladder fungal balls in a premature infant with a combination of three antifungal agents Subscription

Afia Manaf is specialist pharmacist (paediatricsand neonates) at Central Manchester and Manchester Children’sHospital NHS TrustSUMMARY

New antifungal medicine launched

Intravenous therapy with anidulafungin (Ecalta) is a new treatment option for people with fungal blood infections.

New antifungal launched

A new broad spectrum antifungal has been launched by Schering Plough. Posaconazole (Noxafil) is licensed for the treatment of serious refractory invasive fungal infections in patients intolerant to certain other treatments, or in whom they have failed.

New antifungal launched

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New antifungal agent data

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New antifungal agent data

Posaconazole (Noxafil), a new triazole antifungal agent, has demonstrated superior efficacy to fluconazole in preventing aspergillosis in allogeneic haematopoietic stem cell transplant recipients with graft versus host disease.

PJ Online | News | Antifungal lacquer may be P

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Antifungal lacquer may be P

Galderma has applied to the Medicines and Healthcare products Regulatory Agency to have a version of Loceryl antifungal nail lacquer (amorolfine 5 per cent) classified as a pharmacy medicine under the name Curanail Lacquer (PDF 110K).

PJ Online | News | DTB gives cautious welcome to second-line use of two newer antifungal agents ... but criticises transdermal contraceptive patch website

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PJ Online | News: New antifungal for oesophageal candidiasis

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PJ Online | News: Broad-spectrum antifungal for invasive aspergillosis launched

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PJ Online | News: New antifungal launched

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