Category list : Antimicrobial resistance
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Cefiderocol effective for carbapenem-resistant Gram-negative infections Subscription
The clinical and microbiological outcomes of cefiderocol, a new antibiotic, were similar to the best available therapy for patients with life-threatening carbapenem-resistant infections, a phase III study has suggested.
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Stuck in the 1950s: why UTI diagnosis badly needs an update Subscription
Urinary tract infections are the second most common reason for prescribing an antibiotic and, with antimicrobial stewardship a priority for the government, the stakes for accurate diagnosis are being raised ever higher.
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Honey effective at relieving URTI symptoms, analysis concludes Subscription
Honey is superior to usual care for improving symptoms of upper respiratory tract infection symptoms, researchers have concluded.
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Preserving macrolides Subscription
Macrolide antibiotics have many uses, particularly for penicillin-allergic patients, but recent trends suggest that resistance is increasing among Gram-positive infections.
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Point-of-care testing for influenza could improve antimicrobial use, feasibility study concludes Subscription
Point-of-care testing for influenza is feasible in primary care and may improve antimicrobial use, a study in the British Journal of General Practice has concluded.
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Evidence shows the antibiotics market is failing, but here is how it can be revived Subscription
A core group of pharmaceutical companies are making progress in tackling the spread of antimicrobial resistance, but change is not happening at the scale needed to radically impact the threat from drug resistance.
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Pharmacists should make themselves familiar with the Antifungal Drug Interactions Database Subscription
In this time of growing antimicrobial resistance, we do not have unlimited ways to effectively treat a systemic infection. We must be antimicrobial stewards and use antimicrobials responsibly to preserve their effectiveness[1]. This applies to antifungals too — not just antibiotics
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We need a national de-labelling drive for patients with penicillin allergy Subscription
False penicillin allergies are placing patients at risk of resistant infections and are a threat to antimicrobial stewardship; we must safely de-label patients to avoid these costs to public health.
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Dangerous labels: incorrect penicillin allergies fuel antibiotic resistance Subscription
The vast majority of people with a penicillin allergy label are, in fact, not allergic, leading to significant healthcare implications. Experts say it is now time for a national “de-labelling” drive to help conserve vital antibiotics.
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Doubling of penicillin allergy reports may put a million hospital patients at greater risk each year Subscription
An analysis of hospital admissions data by The Pharmaceutical Journal shows that between 2012/2013 and 2018/2019, the number of hospital admissions in England where the patient had a diagnostic ‘label’ of penicillin allergy almost doubled, from 575,000 to 1.1 million.
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'As I listen, I form an action plan' — a day in the life of a patient support officer Subscription
When her son fell chronically ill, Arlene Brailey found the motivation to take on a role dedicated to helping patients with resistant bacterial infections find support and trustworthy information.
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Stopping the spread: ending the resurgence of gonorrhoea Subscription
Incidence of sexually transmitted infections is increasing and antimicrobial resistance is adding fuel to the fire, particularly in the case of gonorrhoea. In response, researchers are working on three major strategies to help reduce its spread and maintain susceptibility to antibiotics.
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Promoting antibiotic guardians in India
English Pharmacy Board member Mahendra Patel on sharing the antimicrobial stewardship message across India, with students and younger pharmacists at the vanguard.
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Tackling antimicrobial resistance in cancer patients at the Christie NHS Foundation Trust Subscription
Antimicrobial resistant (AMR) infections are estimated to cause 700,000 deaths each year globally, and this figure is predicted to rise to 10 million with a cumulative cost of US$100tn by 2050
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Two antimicrobial pharmacists recognised in New Year Honours Subscription
Two pharmacists who have been leading work on protecting against antimicrobial resistance across the NHS have been recognised in the 2020 New Year Honours list.
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Antimicrobials in hospital — a development in advanced e-prescribing analytics Subscription
Rising antimicrobial resistance (AMR) is a recognised threat to global health. There is a perception that poor prescribing practices contribute to the problem, although data confirming this are limited. Reliable data on the quality of antimicrobial prescribing in UK hospitals are not available, with hospital drug-purchasing data most often being used ...
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Pharmacy assessment of penicillin allergy can save money, study finds Subscription
Pharmacy-driven allergy assessments can provide cost savings for patients with a reported penicillin allergy, a study presented at the American Society of Health System Pharmacists’ 54th Midyear Clinical Meeting has shown.
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Governments must make tackling AMR worth pharmacy's while Subscription
Pharmaceutical companies won’t develop fast, cheap and effective diagnostic tools on their own — incentives are the missing piece to tackling antimicrobial resistance.
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More than half of acute trusts are failing to reduce their use of antibiotics Subscription
More than half of acute trusts in England failed to reduce their antibiotic use between 2017/2018 and 2018/2019, according to figures analysed by The Pharmaceutical Journal.
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Secrets of success: the hospitals slashing their antibiotic use Subscription
Despite the rise of resistant infections, national figures show that antibiotic use continues to grow in hospitals. However, some trusts in England are stepping up their stewardship efforts and achieving significant reductions. Here, three trusts share the secrets to their success.
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We must follow these five rules to avert an antimicrobial resistance crisis Subscription
Simply reducing the use of antibiotics, while discovering new ones, is not enough to keep resistance at bay — healthcare professionals need to understand bacteria’s evolutionary biology if they are to subvert it.
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Patients contracted 165 antibiotic resistant infections each day in 2018, says PHE
Patients in England contracted 165 antibiotic resistant infections per day in 2018, a Public Health England report has estimated.
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Little progress made to develop incentives for new antibiotics, vaccines and diagnostics, AMR review concludes
Little progress has been made to transform research or develop incentives for new antibiotics, vaccines and diagnostics, a review of progress on antimicrobial resistance has concluded.
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Antibiotic treatment of Mycoplasma genitalium infection Subscription
An overview of the 2018 guideline for management of this sexually transmitted infection in men and women.
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Emergency antibiotic supplies from pharmacies double in a year Subscription
The number of emergency antibiotics supplied to patients by community pharmacies without a prescription has almost doubled in one year, data from the NHS Business Services Authority show.
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Dame Sally Davies to be first UK special envoy on AMR
England’s outgoing chief medical officer has been appointed as the UK’s first special envoy on antimicrobial resistance.
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WHO urges countries to adopt antibiotic classification tool to protect against AMR
The World Health Organization is encouraging global adoption of a tool designed to reduce the spread of antimicrobial resistance.
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Reductions in antibiotics achievable if guidelines on prescribing duration observed, says NICE
Substantial reductions in antibiotic exposure could be achieved by ensuring that the duration of prescriptions fall in line with national guidance, the National Institute of Health and Care Excellence has said.
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Pharmacists working with global AMR teams made CPO fellows
Some sixteen pharmacists who are part of teams tackling antimicrobial resistance in the developing world have been appointed ‘chief pharmaceutical officer global health fellows’.
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Antibiotic pollution and lack of regulation will have dire global consequences Subscription
Given the hot topic of antimicrobial resistance, one could only be shocked at reading New Scientist’s article ‘How antibiotic resistance is driven by pharmaceutical pollution’ (22 May 2019), which details the prolific dumping of antibiotic ...
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Antibiotic OTC treatments for sore throat could be fuelling antimicrobial resistance, researchers warn Subscription
Over-the-counter treatments that do not contain antibiotics should be considered for the symptomatic management of sore throat to help protect against antimicrobial resistance, researchers have recommended.
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Leading AMR expert calls for state-funded research into new antibiotics Subscription
Establishing state-run drug companies or “utilities” may be the only solution to boost the development of new drugs and win the fight against antimicrobial resistance, according to Lord Jim O’Neill.
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Commonwealth antimicrobial stewardship partnerships announced Subscription
A total of 12 pharmacy-led teams from the UK are set to work with their counterparts in 4 African Commonwealth countries in a bid to exchange expertise in antimicrobial resistance stewardship.
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No-deal Brexit could see UK locked out of EU infectious disease surveillance data, chief medical officer warns Subscription
A no-deal Brexit could see the UK lose access to an EU-wide online tracker of infectious diseases and antimicrobial resistance, Dame Sally Davies, the chief medical officer for England, has told The Pharmaceutical Journal.
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Electronic intervention in GP practices reduces antibiotic prescribing for respiratory infections
Integration of antimicrobial stewardship interventions into GP practices reduces antibiotic prescribing for respiratory infections, research from King’s College London has found.
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More than half of care home residents prescribed at least one antibiotic in a year, Boots study finds Subscription
More than half of older people living in care homes were prescribed at least one antibiotic over a year, a study led by Boots UK has found.
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Pharmacists given greater role in government five-year AMR plan Subscription
The UK government expects pharmacists who work in care homes and GP surgeries to play a greater role in tackling antimicrobial resistance, according to new proposals.
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New antibiotic effective against multi-drug resistant Gram-negative UTI Subscription
A new antibiotic designed to overcome multi-drug resistance is at least as effective as the current standard of care in complicated urinary tract infection, according to trial results published in The Lancet Infectious Diseases.
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UK antibiotic consumption twice that of the Netherlands, WHO report finds
Antibiotic consumption varies hugely in different parts of the world, suggesting overuse in some cases and limited access in others, a report from the World Health Organization has found.
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Antibiotic-resistant bacteria responsible for over 33,000 deaths in Europe in 2015, study finds
Infections with antibiotic-resistant bacteria accounted for over 33,000 deaths across Europe in 2015, researchers from the European Centre for Disease Prevention and Control have calculated.
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Point-of-care testing can support antimicrobial stewardship Subscription
Researchers say the integration of point-of-care testing could help identify lower-risk patients in hospitals and subsequently reduce antibiotic use.
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Antibiotic consumption in England has fallen by 6% in past five years, report shows
Between 2014/2015 and 2017/2018, there were 3.7 million fewer antibiotic prescriptions dispensed from community pharmacies in England, according to the fifth annual report of the English Surveillance Programme for Antimicrobial Utilisation and Resistance.
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Antimicrobial resistance must be 'top five priority' for government, MPs say Subscription
Tackling antimicrobial resistance needs to be firmly established as a ‘top five policy priority’ for the government in order to help prevent the worldwide loss of modern medicine.
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Government provides £32m for innovative antimicrobial resistance research Subscription
Up to £32m of funding will be awarded to the NHS, universities and research organisations for research into antimicrobial resistance, the Department of Health and Social Care has announced.
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Antimicrobial resistance campaign to include all community pharmacies Subscription
Community pharmacists have been given a role to play in a national campaign by Public Health England to fight antimicrobial resistance.
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Pharmacists given funding to tackle global antimicrobial resistance
The government will ring fence £1.34m to support UK pharmacists and nurses working to tackle antimicrobial resistance in Ghana, Tanzania, Uganda and Zambia.
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Pharmacists have critical role in protecting antibiotics by encouraging self-care, GRIP symposium says Subscription
Community pharmacists are central to reducing the inappropriate use of antibiotics in upper respiratory tract infections, according to Martin Duerden, a GP and honorary senior research fellow at Bangor University, Wales.
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Myth-busting sessions in the community to improve knowledge of antimicrobial resistance Subscription
Antimicrobial resistance (AMR) is one of today’s great public health challenges and it is driven by the use of antibiotics. As antimicrobial pharmacists and pharmacy technicians, we are tasked with reducing unnecessary antibiotic use in our patient population at Cwm Taf University Health Board, South Wales, which provides healthcare services to almost 300,000 people living in Merthyr Tydfil and Rhondda Cynon Taf. Like many health organisations, we face the particular challenge of an ...
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AMR will be 'central' to NHS 10-year plan, says minister Subscription
Antimicrobial resistance will be a central element of the NHS 10-year plan, public health and primary care minister Steve Brine told MPs at a House of Commons Health and Social Care Committee hearing on 11 September 2018.
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Patient group direction templates for prescribing antimicrobials should be created, says report
National patient group direction templates for the prescribing of antimicrobial medicines should be developed to save money, boost standards and help in the battle against resistance, according to the NHS Specialist Pharmacy Service.
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