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Concomitant use of antidepressants and non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a significantly increased risk of intracranial haemorrhage (ICH). In the image, axial CT scan of intracranial haemorrhage

Researchers say the addition of NSAIDs to antidepressant treatment increased the risk of intracranial haemorrhage within 30 days of the combination starting.

Source  Wikimedia Commons