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Effectiveness of the different flu vaccines

The WHO coordinates a network called the Global Influenza Surveillance and Response System (GISRS), consisting of 142 National Influenza Centres (NICs) as well as various collaborating centres and laboratories. Recommendations for vaccine composition are made by the WHO in February for the following winter’s flu season in the Northern hemisphere. Antigenic drift of circulating viruses can occur in the interim, leading to a mismatch between the vaccine and circulating strains, and low vaccine effectiveness.

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