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Working towards a universal flu vaccine

Many researchers are trying to create a vaccine that provides broad protection against existing and newly emergent strains, eliminating the need for annual vaccination. Some universal flu vaccines aim to stimulate a cellular immune response, as opposed to the antibody-based response targeted by current vaccines. A cellular response is the mechanism underlying naturally acquired immunity. Even a vaccine more broadly protective within a single subgroup would offer advantages, and could provide some intra-seasonal protection, most likely in combination with conventional vaccines.

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