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Duration of heartburn medications

Antacids: Lasts up to 2 hrs. Neutralises acid. Quick, short term relief of symptoms of occasional heartburn Alginates: Lasts up to 4 hrs. Forms a raft on top of stomach contents. Quick, short term relief of symptoms of occasional heartburn H2 Blockers (i.e. Ranitidine): Lasts up to 12 hrs. Blocks one of the 3 signals that stimulate acid production. Intermediate duration relief of heartburn PPIs (i.e. Esomeprazole): Lasts up to 24 hrs. Acts on proton pumps to reduce acid production. 24hr relief and protection from frequent heartburn which occurs twice per week or more

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