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Hormone replacement therapy (HRT) has a profound impact on the cardiovascular system in postmenopausal women, achieved through its effects on metabolic risk factors for coronary heart disease (CHD) and on arterial function

Publication of the Women's Health Initiative had a major impact on the management of postmenopausal women, as prescribers and regulatory bodies disparaged the use of HRT. However, subsequent data analysis has cast doubt on the initial interpretation of the results.

Source  Cristina Pedrazzini / Science Photo Library