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According to the theory of the researchers, persons on [highly active antiretroviral therapy] HAART for treatment of HIV infection are at higher risk of infection with T pallidum, and perhaps other infectious and noninfectious agents

Syphilis is a sexually transmitted disease that can lead to long-term complications if not treated correctly. Micrograph of T pallidum, the spirochete that causes syphilis.

Source  Nephron / Wikimedia Commons