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Patients aged over 75 who take aspirin-based antiplatelet therapy should be co-prescribed proton-pump inhibitors because of a previously under-recognised risk of serious and disabling upper gastrointestinal bleeding, say the authors of a Lancet study.

Researchers have found that people aged over 75 who take aspirin-based anti platelet therapy have a 2.6-fold increased risk of major non-fatal bleeding and a 5.5-fold increased risk of fatal bleeding