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sections

    Anticoagulation

    The latest learning and CPD content on anticoagulation. Under ‘Other resources’ you will find all our other content related to anticoagulation.

    CPD and Learning

    SEM of activated platelets

    Heparin-induced thrombocytopeniaSubscription

    12 JUL 2017By , ,

    Heparin is widely used for thromboprophylaxis or as a treatment in many clinical situations, however, it can cause serious adverse effects. Heparin-induced thrombocytopenia (HIT), an immune-mediated adverse drug reaction, is associated with high morbidity and mortality if undiagnosed.

    Angiogram of a calf showing deep vein thrombosis

    Prevention of venous thromboembolism in hospitalised patientsSubscription

    5 FEB 2019By

    Pharmacists should note the National Institute for Health and Care Excellence’s updated guidance on use of pharmacological thromboprophylaxis in a range of hospitalised patient groups.

    Other resources

    Gastric bleed

    Forgotten patients: thousands left on risky anticoagulant combinationsSubscription

    29 AUG 2019By

    Combinations of drugs involving anticoagulants are one of the most frequent causes of medicine-related hospital admissions, but pharmacists can help reduce the risk.

    Aspirin tablets close up

    Aspirin increases bleeding risk in patients receiving warfarinSubscription

    18 MAR 2019

    Compared with patients taking warfarin monotherapy, those taking aspirin and warfarin were at a higher risk of a bleeding event but the rate of thrombotic events was similar.

    woman with dementia ss 18

    People with dementia less likely to receive oral anticoagulants despite stroke riskSubscription

    1 OCT 2018

    People with atrial fibrillation who have dementia are less likely to receive oral anticoagulants (OACs) than those without cognitive impairment, research has shown.

    Apixaban molecular structure

    Direct oral anticoagulants carry lower risk of major bleeding versus warfarin, data showSubscription

    13 AUG 2018

    Research from primary care suggests apixaban may be the safest of the direct oral anticoagulants overall.

    Human blood clotting light micrograph

    Andexanet shows promise in patients taking new anticoagulants Subscription

    21 MAY 2018

    Results from an ongoing trial of 228 patients with acute major bleeding show that patients taking andexanet experienced a reduction in anti-FXa activity.

    Cross section of micrograph kidney

    Uncertainty over anticoagulation risks and benefits in CKD patients with AF Subscription

    28 MAR 2018

    The risk of both stroke and haemorrhage increases as chronic kidney disease progresses, which can complicate the decision on whether to begin anticoagulation in those with concomitant atrial fibrillation.

    Warfarin tablet

    Warfarin use associated with lower incidence of cancer in people aged 50 or olderSubscription

    26 JAN 2018

    A Norwegian cohort study finds that warfarin has broad anticancer potential, which could have implications for medication choice for patients needing anticoagulation

    Coloured angiograms (X-rays) taken from the front (left) and side (right) of a leg showing deep vein thrombosis in the calf

    Pharmacomechanical therapy does not lower long-term risks in DVTSubscription

    19 JAN 2018

    A study in The New England Journal of Medicine has shown no significant difference in results following pharmacomechanical therapy for deep-vein thrombosis

    How filgrastim has helped control neutropenia and prevent sepsisSubscription

    17 APR 2014By

    How the granulocyte colony-stimulating factor filgrastim has become part of the staple diet of chemotherapy

    Revalidation

    Pharmacists and pharmacy technicians can find guidance from The Pharmaceutical Journal on completing the relevant records to meet the General Pharmaceutical Council requirements, as well as support on the scope of activity that could be included in these records here.