Acute kidney injury: diagnosis, staging and prevention
Prevention and early recognition of acute kidney injury can improve outcomes for those affected. Pharmacists can help to review patients whose renal function is at risk of rapid deterioration
Around 20% of patients who are admitted to hospital acutely will develop acute kidney injury (AKI). The term describes a rapid deterioration in renal function and is characterised by reduced urine output and increased serum creatinine. The cause of AKI can be pre-renal (eg, hypovolaemia), intrinsic (eg, acute interstitial nephritis) or post-renal (eg, urinary obstruction).
AKI is largely preventable and pharmacists should take steps to optimise medicines for patients at high risk of the condition. This can involve providing advice about avoiding potentially nephrotoxic medicines, monitoring renal function and reviewing medicines.
Sue Shaw is renal pharmacist and Nick Selby is consultant nephrologist, both at Royal Derby Hospital. Adrian Coleman is renal pharmacist at Kent and Canterbury Hospital.
Citation: Clinical Pharmacist URI: 11098637
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