Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.


Subscribe or Register

Existing user? Login

Gout: clinical features and diagnosis

By Mary Duffy, MPharm, and Stephen Hughes, MPharm

Illustration depicting the pain of gout (New York Public Library  Science Photo Library)

During an attack of gout, a person will experience excruciating pain, redness and swelling in one or more peripheral joints. The condition is caused by deposition of urate crystals in the affected joints


Gout is a form of inflammatory arthritis caused by the deposition of urate crystals into the affected joints. The main risk factor for gout is hyperuricaemia, which can be brought about by overproduction or underexcretion of uric acid. 

Gout can be classified into four phases: asymptomatic hyperuricaemia; acute attacks (characterised by the classic symptoms of gout — pain, swelling and erythema of the affected area); interval gout (the symptom-free period between episodes); and chronic tophaceous gout (in which tophi develop in the joints that are affected by repeated, acute episodes). 

Mary Duffy is specialist medical pharmacist and Stephen Hughes is renal pharmacist, both at Central Manchester University Hospitals NHS Foundation Trust.



Citation: Clinical Pharmacist URI: 11096161

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Handbook of Drug Administration via Enteral Feeding Tubes

    Handbook of Drug Administration via Enteral Feeding Tubes

    All you need to know about prescribing or administering drugs via enteral feeding tubes. Over 400 drug monographs as well as facts to inform clinical decision making.

    £54.00Buy now
  • Stockley's Drug Interactions

    Stockley's Drug Interactions

    Now in its twelfth edition, Stockley’s Drug Interactions is still the most comprehensive and authoritative international source of drug interaction information.

    £240.00Buy now
  • Disease Management

    Disease Management

    Disease Management covers the diseases commonly encountered in primary care by system, with common therapeutic issues. Includes case studies and self-assessment sections.

    £54.00Buy now
  • Physicochemical Principles of Pharmacy

    Physicochemical Principles of Pharmacy

    This established textbook covers every aspect of drug properties from the design of dosage forms to their delivery by all routes to sites of action in the body.

    £48.00Buy now
  • Pharmaceutical Toxicology

    Pharmaceutical Toxicology

    Explains the methodology and requirements of pre-clinical safety assessments of new medicines. Includes registration requirements and pharmacovigilance.

    £40.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary information

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.