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New study finds no link between antioxidants and melanoma risk

Vitamin and mineral supplements containing antioxidants are notassociated with an increased melanoma risk, according to new researchpublished

Vitamin and mineral supplements containing antioxidants are not associated with an increased melanoma risk, according to new research published in the Archives of Dermatology (2009;8:879).

The study follows a recent trial — known as SUVIMAX (supplementation in vitamins and mineral antioxidants) — that showed a link between intake of antioxidants and increasing incidence of melanoma in women but not in men.

The new prospective cohort study shows that there is no link between multivitamin use in doses comparable to those used in the SUVIMAX trial and melanoma risk in women (risk ratio 1.14, 95 per cent confidence interval 0.78–1.66) or in men (1.09, 0.83–1.43).

The researchers analysed data from 69,671 adults who took multivitamins and antioxidant supplements, including selenium and beta carotene, for 10 years. They found that neither beta carotene nor selenium was associated with an increased melanoma risk (0.87, 0.48–1.56; 0.98, 0.69–1.41, respectively).

The authors attribute the difference in results from the two studies to shortcomings in the methodology of the SUVIMAX trial.

Citation: The Pharmaceutical Journal URI: 10975988

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