Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

MS drug Zinbryta withdrawn from European market

The relapsing multiple sclerosis treatment Zinbryta (daclizumab beta) has been recommended for immediate suspension and withdrawal from the market by the European Medicines Agency (EMA).

The decision follows 12 reports worldwide of severe immune-mediated brain inflammation in patients taking the drug, three of which were fatal. The drug has also been linked to severe liver damage and immune-mediated disorders.

The EMA announcement means patients currently receiving Zinbryta should have their treatment stopped as soon as possible and be monitored for at least six months, and no new patients should start taking the drug.

The manufacturer Biogen had already requested the EMA withdraw the product’s marketing authorisation and notified them of their intention to cease all clinical trials of the drug. On 2 March 2018, the EMA announced it was launching an urgent review into Zinbryta and has said it will be publishing in-depth findings.

The charity MS-UK said the drug, which received its European marketing authorisation in July 2016, is being used by fewer than 100 patients in the UK.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2018.20204516

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Drugs of Abuse

    Drugs of Abuse

    A concise, easy-to-read guide for healthcare professionals who encounter drug abuse.

    £38.00Buy now
  • Adverse Drug Reactions

    Adverse Drug Reactions

    A practical guide to the drug reactions that affect particular organ systems, and the management of these reactions.

    £38.00Buy now
  • Applications of LC-MS in Toxicology

    Applications of LC-MS in Toxicology

    Practical, hands-on information on the application of LC-MS in the field of toxicology.

    £140.00Buy now
  • English Delftware Drug Jars

    English Delftware Drug Jars

    This beautiful book illustrates the art and history of the collection of English delftware drug jars in the Museum of the Royal Pharmaceutical Society of Great Britain.

    £54.00Buy now
  • Paediatric Drug Handling

    Paediatric Drug Handling

    Written for new pharmaceutical scientists, this book provides a background in paediatric pharmacy and a comprehensive introduction to children's medication.

    £33.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • European Medicines Agency building in Canary Wharf, London

Jobs you might like

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.