Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Whistleblowing

NHS Tayside pharmacists felt 'professionally vulnerable' drug dosing concerns were ignored

Following controversy around the dose reduction of breast cancer medicine docetaxel, a report by Health Improvement Scotland recommends that NHS Tayside considers work to improve multiprofessional team working to ensure all its voices are heard.

NHS Tayside report by Health Improvement Scotland

Source: Health Improvement Scotland

The Health Improvement Scotland report recommends that NHS Tayside “consider further work to improve multiprofessional team working” after concerns were raised about changing the baseline dosage of chemotherapy drug docetaxel

Pharmacists at NHS Tayside said they felt “professionally vulnerable” after changes to breast cancer drug dosing were introduced by a consultant breast cancer oncology team, a report by Health Improvement Scotland (HIS) has found.

Among the changes, which were decided by NHS Tayside’s clinical oncology team and implemented in December 2016, was reducing the baseline dose of chemotherapy drug docetaxel down from the widely prescribed 100mg per m2 to 75mg per m2.

According to the report, the dosage change differed from practice at other NHS health boards where “patients would receive 100mg per m2 as a baseline, with dosages reduced, or an alternative evidence-based regimen used if necessary, to meet individual patients’ needs”.

“However, in NHS Tayside, all patients would receive the lower dosage. Some members of the multiprofessional team described the situation as a differing interpretation of existing evidence, or selective consideration of the evidence,” the report added.

The lead pharmacist on the Oncology and Haematology Medicines Management Group — a subgroup of NHS Tayside’s Area Drug and Therapeutics Committee — used the board’s whistleblowing procedure to question the evidence base behind this decision.

The HIS report, published on 1 April 2019, said: “In response [to the concerns raised], they were advised by email that ‘the decision on what chemotherapy and other supportive treatments to give is one for the consultant oncologists’.” 

It added that the wider multidisciplinary team at NHS Tayside, including pharmacists and nurses, “also expressed concern that the practice is different to other centres and networks”.

As a result of the decision to reduce dosage, the report said: “Pharmacy and nursing staff indicated that they had felt professionally vulnerable as a result of the change to practice and took steps to seek assurance from their respective senior managers to ensure they had organisational protection to continue delivering the prescribed regimens for neo-adjuvant and adjuvant treatments for breast cancer.”

However, the report added that the NHS Tayside breast cancer oncology consultant team were “firm in their belief that their practice is in the best interests of patients in NHS Tayside”, and that the higher doses were not well tolerated in their patient population.

The oncology team told HIS that they had undertaken an audit, which had shown “unacceptable rates of neutropenic sepsis” when 100mg docetaxel per m2 were used.

The HIS panel, which produced the report, was informed of a separate audit carried out by the pharmacy team which, according to some staff, supported the whistleblower’s concerns. However, the audit was “discounted by the NHS Tayside breast oncologists as, in their view, the methodology was flawed”.

The panel also said that they heard “from a number of professionals that any debate on this issue was stifled due to the ongoing response to the whistleblower’s concerns”.

The HIS report added: “There appears to be a culture within the team where the multiprofessional voice is not being heard.”

As a result, the report recommends that NHS Tayside “consider further work to improve multiprofessional team working”.

Responding to the report, Alex MacKinnon, director of the Royal Pharmaceutical Society Scotland, said it is “essential that health boards work to improve their whistleblowing policies within healthcare, including pharmacy, and provide support and protection to staff who raise concerns”.

“People will not speak up if they fear retaliation or they think that to do so would be futile. Healthcare professionals should feel able to act in the best interests of their patients at all times.”

Rose Marie Parr, chief pharmaceutical officer for Scotland, added: “I recognise that some of the findings of this report are matters of concern. NHS Tayside will now consider what further work might be required to improve multiprofessional team working, and to ensure that the voice of all the professions is properly heard.

“This work with be supported by the expert group commissioned by the chief medical officer and led by Professor Aileen Keel.”

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2019.20206381

Readers' comments (1)

  • As I understand this (and it has needed some very careful reading), this is the first time in over 50 years in pharmacy that I have seen pharmacy put its head over the parapet, and speak out (ok, with the help of the nurses: extraordinary!). Perhaps there really is something to be said for 'clinical pharmacy', other than just running a 'give people what they want' outfit. 'Professionally vulnerable': I never believed that I would live to see pharmacy using such an expression! More please!

    Unsuitable or offensive? Report this comment

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.