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Advice on ibuprofen will be updated in Europe following final approval by the Co-ordination Group for Mutual Recognition and Decentralised Procedures – Human (part of the European Medicines Agency). Updated advice was recommended by the Pharmacovigilance Risk Assessment Committee (PRAC) following a review by PRAC that confirmed an increased risk of cardiovascular problems at doses at or above 2,400mg of ibuprofen a day. Higher doses of ibuprofen should be avoided in patients with underlying ...
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