Amias can be used with ACE inhibitors
The summary of product characteristics (SPC) for Amias (candesartan cilexetil; Takeda) now states that the product can be used to treat adult patients with heart failure and impaired left ventricular systolic function when angiotensin converting enzyme (ACE) inhibitors are not tolerated or as add-on therapy to ACE inhibitors in patients with symptomatic heart failure, despite optimal therapy, when mineralocorticoid receptor antagonists are not tolerated. Additional warnings related to the use of Amias with ACE inhibitors have also been added to the SPC.
Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2014.20067308
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