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November 2015: SMC decisions

The Scottish Medicines Consortium has accepted the following medicines for use in NHS Scotland: atazanavir and cobicistat (Evotaz; Bristol-Myers Squibb); edoxaban (Lixiana; Daiichi Sankyo), for two separate indications; pembrolizumab (Keytruda; Merck Sharp and Dohme), as monotherapy for the treatment of advanced (unresectable or metastatic) melanoma in adults previously untreated with ipilimumab; tiotropium/olodaterol (Spiolto Respimat; Boehringer Ingelheim); and triamcinolone hexacetonide (Intrapharm).

Bevacizumab (Avastin; Roche) and raltegravir chewable tablets and granules for oral suspension (Isentress; Merck Sharp and Dohme) have been accepted for restricted use.

Everolimus (Certican; Novartis), pembrolizumab (Keytruda; Merck Sharp and Dohme), as monotherapy for the treatment of advanced (unresectable or metastatic) melanoma in adults previously treated with ipilimumab, and regorafenib (Stivarga; Bayer) are not recommended for use in NHS Scotland.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2015.20200070

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