NSAIDs in early pregnancy not linked with miscarriage
Non-steroidal anti-inflammatory drug use in early pregnancy is not associated with an increased risk of miscarriage, according to a study published in Obstetrics and Gynecology (July 2012;120:113).
The study looked at data for 2,780 women, who were interviewed in their first trimester between 2004 and 2010. NSAID use was reported by 43 per cent of women. In total, 367 of the women (13 per cent) had a miscarriage.
No association was found between over-the-counter NSAID exposure and miscarriage risk (unadjusted hazard ratio 1.01, 95 per cent confidence interval 0.82–1.24). An association was found between salicylates use and increased miscarriage risk, although this was not statistically significant, the authors say.
Citation: The Pharmaceutical Journal URI: 11103430
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