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Paroxetine affects personality as well as easing depression

Paroxetine has an effect on the personality of patients with depression separate to its effect of alleviating depression, according to the authors of new research (Archives of General Psychiatry 2009;66:1322).

In a trial of 240 patients with major depressive disorder, those assigned to paroxetine were more likely to report a reduction in neurotic symptoms and an increase in symptoms suggestive of extraversion, compared with those assigned to placebo. All patients showed improvement in their symptoms of depression.

Citation: The Pharmaceutical Journal URI: 10989078

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