Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Atrial fibrillation

Atrial fibrillation patients not receiving guideline-recommended drugs to reduce stroke risk

Retrospective data analysis results show that the 16% of patients who were given anticoagulant prior to stroke showed reduction in stroke severity, lower odds of mortality and better functional outcomes.

Atrial fibrillation (AF) accounts for 10–15% of all ischaemic strokes. US clinical guidelines recommend that anticoagulation therapies, such as warfarin or non-vitamin K antagonist oral anticoagulants, are given to patients with AF to help prevent stroke, but they are generally underused in community practice.

Researchers from the Duke Clinical Research Institute in North Carolina retrospectively analysed 94,474 older adults with acute ischaemic stroke and a known history of AF, discovering that 84% did not receive guideline-recommended therapeutic anticoagulation treatment prior to having a stroke.

Of the 16% who were given anticoagulation prior to stroke, the researchers found that there was a significant reduction in stroke severity, lower odds of in-hospital mortality, and better functional outcomes.

Publishing their findings in JAMA[1] (online, 14 March 2017), the researchers conclude that a substantial number of strokes may result from underuse of or inadequate anticoagulation in AF.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20202458

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Electrocardiogram machine

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.