Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Analgesics

Capsaicin patch as effective as pregabalin for peripheral neuropathic pain

Head-to-head study shows capsaicin patch is just as effective for peripheral neuropathic pain as standard pregabalin treatment. 

A head-to-head study has found that the capsaicin patch is as effective as pregabalin for peripheral neuropathic pain (PNP). In the image, a woman holds her wrist in pain

Source: Shutterstock.com

Peripheral neuropathic pain could be treated with capsaicin patches as an alternative to pregabalin

Pregabalin is the standard of care for peripheral neuropathic pain (PNP), but it can cause side effects that sometimes result in dose restrictions or discontinuation. The capsaicin patch is a potential alternative treatment, but it has never been directly compared with other treatments for PNP. 

Now a head-to-head study has found that the capsaicin patch is as effective as pregabalin for treating PNP. After eight weeks, 282 patients receiving the capsaicin 8% patch were as likely to achieve a ≥30% decrease in pain score as 277 patients receiving an optimised dose of oral pregabalin. 

Patients in the pregabalin group also experienced more systemic side effects, such as nausea and dizziness, while most side effects in the capsaicin group were related to the application site, the researchers report in the European Journal of Pain (online, 19 November 2015)[1].

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2015.20200225

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • A head-to-head study has found that the capsaicin patch is as effective as pregabalin for peripheral neuropathic pain (PNP). In the image, a woman holds her wrist in pain

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.