Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.


Subscribe or Register

Existing user? Login


HIV PrEP needs licensing for adolescents, researchers say

Study highlights a need for adolescent men who have sex with men to be given pre-exposure prophylaxis and for adherence to be promoted in this group.

The efficacy of pre-exposure prophylaxis (PrEP; tenofovir disoproxil fumarate/emtricitabine) against HIV transmission has never been explored in adolescents, despite them being a major group at risk of the virus.

In a study in JAMA Pediatrics (online, 5 September 2017), researchers enrolled 78 HIV-negative men who have sex with men aged 15–17 years, who were at high-risk for acquiring the virus. They received PrEP and took part in an HIV prevention intervention over 48 weeks[1].

The researchers found that the drug was well tolerated and adherence was high during the first three months (49% at week 12) of the study, but declined as time went on (22% at week 48). Three participants acquired an HIV infection during the study follow-up, all of whom had low detectable drug levels.

The researchers said that the level of HIV transmission, which was higher than in other studies, indicates the need for PrEP in this age group but more resources may be needed to promote adherence.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20203689

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Pre-exposure prophylaxis (PrEP) pills spilling from Truvada bottle

Jobs you might like

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.