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Imported generics as effective as branded antivirals for hepatitis C

Hepatitis C infection was undetectable in 98% of patients after treatment with generic antivirals.

Micrograph of Hepatitis C virus

Source: BSIP SA / Alamy Stock Photo

Results for generic hepatitis C medicines were comparable to those seen in phase III trials of branded treatments

Access to antiviral therapy for hepatitis C infection is restricted in some countries due to the high cost of branded drugs.

Researchers in Australia, where patients can legally import a three-month supply of treatment, studied the efficacy of imported generic antivirals in 419 patients with hepatitis C infection.

Their interim results show that the virus was undetectable in 98% of patients at the end of treatment, and in 96% of patients four weeks after stopping treatment.

The researchers, who reported their findings at the International Liver Congress in April 2016[1], said the results are comparable to those seen in phase III trials of branded treatments. They added that improving access to these cheaper generic drugs could therefore have a major impact on hepatitis C treatment around the world.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2016.20201038

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Supplementary images

  • Micrograph of Hepatitis C virus

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