Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Adverse drug events

Long-term antiepileptic drug use may impair balance

Study finds long-term users of antiepileptic medication had poorer static balance.

Antiepileptic medication use appears to be associated with poorer balance control, but it’s not clear if these effects are related to epilepsy itself or its treatment. In the image, close-up of the feet of a young person walking down a street

Source: Shutterstock.com

Antiepileptic therapy may progressively impair balance mechanisms, say researchers

Antiepileptic medication use appears to be associated with poor balance control, but it is not clear if these effects are related to epilepsy itself or its treatment.

Researchers from the University of Melbourne, Australia, studied 26 pairs of twins or siblings, where one had received long-term treatment for a condition requiring antiepileptic medication (median 19 years) and the other had not.

The study found that, at baseline and follow-up, users of antiepileptic medication had more body sway and poorer static balance than non-users. Over a median of three years, the patients also had a significantly greater annual deterioration in sway than their twin and sibling controls.

The researchers, writing in the November issue of Epilepsia[1], say that antiepileptic therapy may therefore progressively impair balance mechanisms, although further studies are required to exclude confounding factors.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2015.20200113

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Patient Care in Community Practice

    Patient Care in Community Practice

    Patient Care in Community Practice is a unique, practical guide for healthcare professionals or carers. Covers a range of non-medicinal products suitable for use at home.

    £22.00Buy now
  • Clinical Pharmacokinetics

    Clinical Pharmacokinetics

    A practical guide to the use of pharmacokinetic principles in clinical practice. Includes case studies with questions and answers.

    £33.00Buy now
  • Drugs of Abuse

    Drugs of Abuse

    A concise, easy-to-read guide for healthcare professionals who encounter drug abuse.

    £38.00Buy now
  • Strategic Medicines Management

    Strategic Medicines Management

    A practical guide to influencing the availability of medicines, and policies of their use. Focuses on the strategic elements of medicines management.

    £33.00Buy now
  • Adverse Drug Reactions

    Adverse Drug Reactions

    A practical guide to the drug reactions that affect particular organ systems, and the management of these reactions.

    £38.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Antiepileptic medication use appears to be associated with poorer balance control, but it’s not clear if these effects are related to epilepsy itself or its treatment. In the image, close-up of the feet of a young person walking down a street

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.